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At IMB, we explore the molecular biology of the nucleus with an overarching focus on gene regulation, epigenetics & genome stability

University Medical Center (UMC) Mainz

Christian Behl  Benedikt Berninger  Luciana Berod  Tobias Bopp  Andreas Daiber  Sven Danckwardt  Carsten Deppermann  Stephan Grabbe  Thomas Hofmann  Daniela Kramer  Daniela Krause  Dilja Krueger-Burg  Michael Kühn  Beat Lutz  Johannes Mayer  Wolfram Ruf  Katrin Schäfer  Susann Schweiger  Natalia Soshnikova  Tim Sparwasser  Oliver Tüscher  Sara Vieira-Silva  Ari Waisman  Philipp Wild  Jennifer Winter  Fatemeh Zare-Shahneh 

Systems medicine – a holistic approach to promoting healthy ageing

Philipp Wild

The Systems Medicine Group has comprehensive experience in molecular epidemiology and systems medicine research. We focus on investigating complex common diseases, which are strongly driven by the ageing process. Our research themes range from cardiovascular diseases, such as thrombotic disease and heart failure, to cardiometabolic conditions including obesity and type 2 diabetes mellitus, infectious diseases with system-wide sequelae (more specifically COVID-19 and post-COVID syndrome) and cancers. The study of how the ageing process induces pathological changes is highly clinically relevant and a key priority for our group.

Research website

Positions held

  • Since 2024: Researcher, German Cancer Consortium (DKTK) 
  • Since 2022: Board Member of the Mainzer Herz Foundation 
  • Since 2022: PI Systems Medicine (Adjunct Clinician), Institute of Molecular Biology (IMB)
  • Since 2020: Deputy Site Speaker RheinMain, German Center for Cardiovascular Research (DZHK)
  • Since 2015: Head of Liquid Biobank, UMC, Mainz
  • Since 2015: Speaker, Research Center for Translational Vascular Biology (CTVB), UMC, Mainz
  • Since 2014: W3-Professor of Clinical Epidemiology, Center for Thrombosis and Hemostasis Mainz (CTH), UMC, Mainz
  • Since 2013: Head of Preventive Cardiology and Preventive Medicine, Center for Cardiology, UMC, Mainz
  • Since 2012: Head of Clinical Epidemiology and Systems Medicine, Center for Thrombosis and Hemostasis (CTH), UMC, Mainz
  • 2012 – 2014: W2-Professor of Clinical Epidemiology, Center for Thrombosis and Hemostasis (CTH), UMC, Mainz
  • Since 2011: Coordinating Principal Investigator and Steering Committee Member of the Gutenberg Health Study (GHS), UMC, Mainz
  • 2010 – 2012: Senior Physician, Dept. of Medicine 2, UMC, Mainz

Education

  • 2022: Board certification in Cardiology
  • 2019: Clinical Trial Management (CTM)
  • 2012: MSc in Epidemiology, IMBEI, University Medical Center (UMC), Mainz
  • 2009: Board certification in Internal Medicine
  • 2004: MD, Philipps University Marburg
  • 2002: Medical School, University Leipzig and Medical School, Philipps University Marburg

Selected publications by Philipp Wild

Wild PS and Zeller T (2025) From locus to lipase: LIPA as a paradigm for post-GWAS mechanistic and translational research in CAD. Eur Heart J, 46:5289-5291 Link

Baumkötter R, Yilmaz S, Chalabi J, Ten Cate V, Mamoor Alam AS, Golriz Khatami S, Zahn D, Hettich-Damm N, Prochaska JH, Schmidtmann I, Lehnert K, Steinmetz A, Dörr M, Pfeiffer N, Münzel T, Lackner KJ, Beutel ME and Wild PS (2025) Risk tools for predicting long-term sequelae based on symptom profiles after known and undetected SARS-CoV-2 infections in the population. Eur J Epidemiol, 40:789-801 Link

Panova-Noeva M, Koeck T, Schoelch C, Schulz A, Prochaska JH, Michal M, Strauch K, Schuster AK, Lackner KJ, Münzel T, Hennige AM and Wild PS (2024) Obesity-related inflammatory protein signature in cardiovascular clinical outcomes: Results from the Gutenberg Health Study. Obesity, 32:1198–1209 Link

Ten Cate V, Rapp S, Schulz A, Pallares Robles A, Jurk K, Koeck T, Espinola-Klein C, Halank M, Seyfarth HJ, Beutel ME, Schuster AK, Marini F, Hobohm L, Lankeit M, Lackner KJ, Ruf W, Münzel T, Andrade-Navarro MA, Prochaska JH, Konstantinides SV and Wild PS (2023) Circulating microRNAs predict recurrence and death following venous thromboembolism. J Thromb Haemost, 21:2797-2810 Link

Krolevets M, Cate VT, Prochaska JH, Schulz A, Rapp S, Tenzer S, Andrade-Navarro MA, Horvath S, Niehrs C and Wild PS (2023) DNA methylation and cardiovascular disease in humans: a systematic review and database of known CpG methylation sites. Clin Epigenetics, 15:56 Link

For a full list of publications, please see: Praeventive Medizin » About Us » Head of Department » Publications (unimedizin-mainz.de)