Hohmann Lab
Research Publications Group Members Biography2024
Baumgartner L, Ipsaro JJ, Hohmann U, Handler D, Schleiffer A, Duchek P and Brennecke J (2024) Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals. eLife, 13:1674-1688 Link
Bugai A*, Hohmann U*, Lorenzo A*, Graf M*, Fin L, Rouviere J, Tirian L, Dou Y, Polak P, Johnsen D, Jakobsen L, Andersen JS, Brennecke J°, Plaschka C° and Jensen TH° (2025) Molecular basis of polyadenylated RNA fate determination in the nucleus. bioRxiv, doi: 10.1101/2025.09.16.676470 *indicates joint contribution, °indicates joint senior author Link
Hohmann U, Graf M, Schellhaas U, Pacheco-Fiallos B, Fin L, Riabov-Bassat D, Pühringer T, Szalay M, Tirián L, Handler D, Brennecke J and Plaschka C (2024) A molecular switch orchestrates the nuclear export of human messenger RNA. bioRxiv, doi: 10.1101/2024.03.24.586400 Link
Obergfell E, Hohmann U, Moretti A, Chen H and Hothorn M (2024) Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling in Arabidopsis. Plant Cell Physiol, 65:1674-1688 Link
2023
Neubus Claus LA, Liu D, Hohmann U, Vukašinović N, Pleskot R, Liu J, Schiffner A, Jaillais Y, Wu G, Wolf S, Van Damme D, Hothorn M and Russinova E (2023) BRASSINOSTEROID INSENSITIVE1 internalization can occur independent of ligand binding. Plant Physiol, 192:65-76 Link
2021
Parys K*, Colaianni NR*, Lee H*, Hohmann U, Edelbacher N, Trgovcevic A, Blahovska Z, Lee D, Mechtler A, Muhari-Portik Z, Madalinski M, Schandry N, Rodríguez-Arévalo I, Becker C, Sonnleitner E, Korte A, Bläsi U, Geldner N, Hothorn M, Jones CD, Dangl JL and Belkhadir Y (2021) Signatures of antagonistic pleiotropy in a bacterial flagellin epitope. Cell Host Microbe, 29:620-634.e9 *indicates joint contribution Link
Schnabl J, Wang J, Hohmann U, Gehre M, Batki J, Andreev VI, Purkhauser K, Fasching N, Duchek P, Novatchkova M, Mechtler K, Plaschka C, Patel DJ and Brennecke J (2021) Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex. Genes Dev, 35:392-409 Link
2020
Hohmann U, Ramakrishna P, Wang K, Lorenzo-Orts L, Nicolet J, Henschen A, Barberon M, Bayer M and Hothorn M (2020) Constitutive activation of leucine-rich repeat receptor kinase signaling pathways by BAK1-INTERACTING RECEPTOR-LIKE KINASE3 chimera. Plant Cell, 32:3311-3323 Link
Okuda S, Fujita S, Moretti A, Hohmann U, Doblas VG, Ma Y, Pfister A, Brandt B, Geldner N and Hothorn M (2020) Molecular mechanism for the recognition of sequence-divergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2. Proc Natl Acad Sci USA, 117:2693-2703 Link
Pühringer T*, Hohmann U*, Fin L, Pacheco-Fiallos B, Schellhaas U, Brennecke J and Plaschka C (2020) Structure of the human core transcription-export complex reveals a hub for multivalent interactions. eLife, 9:e61503 *indicates joint contribution Link
2019
Hohmann U and Hothorn M (2019) Crystal structure of the leucine-rich repeat ectodomain of the plant immune receptor kinase SOBIR1. Acta Crystallogr D Struct Biol, 75:488-497 Link
Lorenzo-Orts L, Hohmann U, Zhu J and Hothorn M (2019) Molecular characterization of CHAD domains as inorganic polyphosphate-binding modules. Life Sci Alliance, 2:e201900385 Link
ElMaghraby MF, Andersen PR, Pühringer F, Hohmann U, Meixner K, Lendl T, Tirian L and Brennecke J (2019) A heterochromatin-specific RNA export pathway facilitates piRNA production. Cell, 178:964-979.e20 Link
2018
Hohmann U, Santiago J, Nicolet J, Olsson V, Spiga FM, Hothorn LA, Butenko MA and Hothorn M (2018) Mechanistic basis for the activation of plant membrane receptor kinases by SERK-family coreceptors. Proc Natl Acad Sci USA, 115:3488-3493 Link
Hohmann U, Nicolet J, Moretti A, Hothorn LA and Hothorn M (2018) The SERK3 elongated allele defines a role for BIR ectodomains in brassinosteroid signalling. Nat Plants, 4:345-351 Link
Hohmann U and Hothorn M (2018) Brassinosteroid sensing and signaling in plants. Pages 149-164 in: Plant Structural Biology: Hormonal Regulations (eds. Hejátko J & Hakoshima T), Springer, Cham, Switzerland Link
2017
Hohmann U, Lau K and Hothorn M (2017) The structural basis of ligand perception and signal activation by receptor kinases. Annu Rev Plant Biol, 68:109-137 Link
2016
Santiago J, Brandt B, Wildhagen M, Hohmann U, Hothorn LA, Butenko MA and Hothorn M (2016) Mechanistic insight into a peptide hormone signaling complex mediating floral organ abscission. eLife, 5:e15075 Link