At IMB, we explore the molecular biology of the nucleus with an overarching focus on gene regulation, epigenetics & genome stability
Welcome to IMB! We are a modern research centre that brings together leading scientists from all over the world. Our researchers tackle ambitious projects at the interface of epigenetics, genome stability, ageing & RNA biology.
- About us
Who we are, where we are & what we do...
- Research
Our scientists & what they are working on...
- Core Facilities
State-of-the-art technologies & services...
- Students & Postdocs
Training programmes we offer junior researchers...
- Seminars & Events
Conferences, meetings, workshops & more...
- Careers
Current opportunities at IMB...
Recent Publications
- Jun 2025 | ChemMedChem | StelzlProton first: rationalizing a proton transfer in a protein-fragment complex.
- Jun 2025 | Genes Dev | Keller ValsecchiSex-specific transcriptome dynamics of Anopheles gambiae during embryonic development.
- May 2025 | DNA Repair | UlrichReversible association of ubiquitin with PCNA is important for template switching in S. cerevisiae.
- May 2025 | EMBO Rep | LukeRNase H1 and Sen1 ensure that transient TERRA R-loops promote the repair of short telomeres.
- May 2025 | Nat Commun | Stelzl | DormannMolecular simulations of enzymatic phosphorylation of disordered proteins and their condensates.
- May 2025 | Nat Commun | DormannStructural basis of phosphorylation-independent nuclear import of CIRBP by TNPO3.
- May 2025 | J Exp Zool B Mol Dev Evol | Keller ValsecchiMultiomics reveal associations between CpG methylation, histone modifications and transcription in a…
- Apr 2025 | Nat Chem Biol | DormannInduced proximity to PML protects TDP-43 from aggregation via SUMO-ubiquitin networks.
- Apr 2025 | Curr Opin Struct Biol | LuckBias in, bias out - AlphaFold-Multimer and the structural complexity of protein interfaces.
- Mar 2025 | Science | BeliPathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy.
Joint Research Initiatives
A centre for basic & clinical research on ageing & age-related disease
A joint initiative on the mechanisms underlying robustness & longevity
A joint PhD programme to discover new ways to understand & treat age-related diseases
The largest network on DNA repair & genome stability in Germany
An initiative bridging the polymer & life sciences to understand biological processes such as ageing
IMB’s flagship PhD training programme on epigenetics, genome stability & ageing
A DFG-funded PhD programme on how RNA processes contribute to robustness & resilience
A DFG-funded PhD programme on the evolution of gene regulatory networks underlying phenotype & lifespan
IMB's summer school on epigenetics & genome stability in health, ageing & disease, for Master & undergraduate students