PhD projects offered
The IPP offers a wide range of research topics in the participating groups located at the Institute of Molecular Biology (IMB), Johannes Gutenberg University (JGU) and the University Medical Center Mainz (UMC) but not every group participating in the IPP offers a position in every call.
Below you can find a list of group leaders offering a position in the current IPP call and descriptions of the offered PhD projects. Be aware that projects may appear several times if they fit into different research topics.
If you are interested in applying to one or more of the projects below, apply until 19 April 2023 (12:00 noon CEST). Guidelines for registration and application can be found here.
Ageing & Disease
Bioinformatics & Computational Biology
| Group Leader | Topic | Institution |
|---|---|---|
| Shuqing Xu | Evolution of metabolic novelty in plants | JGU |
| Helle Ulrich | Ubiquitin, SUMO & Genome Maintenance | IMB |
| Wolfram Ruf | Thrombo-inflammatory Roles of Megakaryocytes and Platelets | UMC |
| Sara Vieira-Silva | Perturbation, recovery and resilience of the human gut microbiota | UMC |
| Petra Beli | Targeted protein degradation in nuclear quality control centers | JGU/IMB |
| Claudia Keller Valsecchi_Anoph | Sex Chromosome Regulation in Malaria Mosquitos | IMB |
| Stamatis Papathanasiou_Transcr | Genome architecture and transcription dysregulation due to abnormal mitosis | IMB |
DNA Repair & Genome Stability
| Group Leader | Topic | Institution |
|---|---|---|
| Vassilis Roukos/Petra Beli | Sources and consequences of intrinsic genomic instability across human cell types | IMB/JGU |
| Helle Ulrich | Ubiquitin, SUMO & Genome Maintenance | IMB |
| Petra Beli | Targeted protein degradation in nuclear quality control centers | JGU/IMB |
| Brian Luke | R-loops, telomeres and senescence | JGU |
| Stamatis Papathanasiou_CSD | Chromatin state dysregulation due to abnormal mitosis | IMB |
| Sven Danckwardt | Dynamics of transcriptome 3’end diversity in development and disease | UMC |
| Peter Baumann | RNA as master regulator of telomere maintenance and life span | JGU/IMB |
| Julian König | The interplay between RNA splicing and R-loop formation | IMB |
| Thomas Hofmann | A role of Casp8AP2 in R-loop regulation and the DNA damage response | UMC |
| Dorothee Dormann | Molecular mechanisms of RNA-binding protein dysfunction in neurodegenerative disorders | JGU/IMB |
| Thomas Hofmann | DNA damage signaling, DNA repair & cell fate control | UMC |
Epigenetics & Nuclear Dynamics
| Group Leader | Topic | Institution |
|---|---|---|
| Jan Padeken | Understanding the epigenetic regulators of noise affecting aging and cellular resilience | IMB |
| Christof Niehrs_Ageing | Embryos, Ageing & Epigenetics | IMB |
| Sina Wittmann | The Role of Protein Condensation in Gene Activation and its Contribution to Cancer | IMB |
| Michael Kühn | Targeting Chromatin Regulators in Leukemia | UMC |
| René Ketting_Rloop | R-loop function in nuclear RNAi | IMB |
| Christof Niehrs_Rloop | DNA:RNA hybrids in epigenetic regulation | IMB |
| Stamatis Papathanasiou_CSD | Chromatin state dysregulation due to abnormal mitosis | IMB |
| Stamatis Papathanasiou_Transcr | Genome architecture and transcription dysregulation due to abnormal mitosis | IMB |
| Julian König | The interplay between RNA splicing and R-loop formation | IMB |
| René Ketting_Hist | Histone mRNA homeostasis in early embryos | IMB |
Gene Regulation & Evolution
| Group Leader | Topic | Institution |
|---|---|---|
| Shuqing Xu | Evolution of metabolic novelty in plants | JGU |
| Sina Wittmann | The Role of Protein Condensation in Gene Activation and its Contribution to Cancer | IMB |
| Claudia Keller Valsecchi_Anoph | Sex Chromosome Regulation in Malaria Mosquitos | IMB |
| Claudia Keller Valsecchi_Rloop | Gene Dosage, R-Loops and Splicing Paralogues | IMB |
| Stamatis Papathanasiou_Transcr | Genome architecture and transcription dysregulation due to abnormal mitosis | IMB |
| Sven Danckwardt | Dynamics of transcriptome 3’end diversity in development and disease | UMC |
| René Ketting_Hist | Histone mRNA homeostasis in early embryos | IMB |
RNA Biology
| Group Leader | Topic | Institution |
|---|---|---|
| Helle Ulrich | Ubiquitin, SUMO & Genome Maintenance | IMB |
| Claudia Keller Valsecchi_Rloop | Gene Dosage, R-Loops and Splicing Paralogues | IMB |
| René Ketting_Rloop | R-loop function in nuclear RNAi | IMB |
| Brian Luke | R-loops, telomeres and senescence | JGU |
| Christof Niehrs_Rloop | DNA:RNA hybrids in epigenetic regulation | IMB |
| Sven Danckwardt | Dynamics of transcriptome 3’end diversity in development and disease | UMC |
| Peter Baumann | RNA as master regulator of telomere maintenance and life span | JGU/IMB |
| Julian König | The interplay between RNA splicing and R-loop formation | IMB |
| Thomas Hofmann | A role of Casp8AP2 in R-loop regulation and the DNA damage response | UMC |
| Dorothee Dormann | Molecular mechanisms of RNA-binding protein dysfunction in neurodegenerative disorders | JGU/IMB |
| Andreas Wachter | Regulation and functions of alternative splicing in plants | JGU |
| Susann Schweiger | Finding a therapy for Huntington’s Disease | UMC |
| René Ketting_Hist | Histone mRNA homeostasis in early embryos | IMB |