2017

Bicker F, Vasic V, Horta G, Ortega F, Nolte H, Kavyanifar A, Keller S, Stankovic ND, Harter PN, Benedito R, Lutz B, Bäuerle T, Hartwig J, Baumgart J, Krüger M, Radyushkin K, Alberi L, Berninger B and Schmidt MHH (2017) Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception. Nat Commun, 8:15922 Link

De Azua IR, Mancini G, Srivastava RK, Rey AA, Cardinal P, Tedesco L, Zingaretti CM, Sassmann A, Quarta C, Schwitter C, Conrad A, Wettschureck N, Vemuri VK, Makriyannis A, Hartwig J, Mendez-Lago M, Bindila L, Monory K, Giordano A, Cinti S, Marsicano G, Offermanns S, Nisoli E, Pagotto U, Cota D and Lutz B (2017) Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages. J Clin Invest, 127:4148–4162 Link

2015

Seo EJ, Wiench B, Hamm R, Paulsen M, Zu Y, Fu Y and Efferth T (2015) Cytotoxicity of natural products and derivatives toward MCF-7 cell monolayers and cancer stem-like mammospheres. Phytomedicine, 22:438–443 Link

Zeino M, Paulsen M, Zehl M, Urban E, Kopp B and Efferth T (2015) Identification of new P-glycoprotein inhibitors derived from cardiotonic steroids.Biochem Pharmacol, 93:11–24 Link

2014

Holloschi A, Ritz S, Schäfer I and Kioschis P (2014) Analysis of huntingtin aggregation by fluorescence and FRET microscopy. Pages 217–215 in: Microscopy: Advances in scientific research and education, vol. 1 (ed. Méndez-Vilas A), Formatex, Badajoz  Link

2013

Wiench B, Chen YR, Paulsen M, Hamm R, Schröder S, Yang N-S and Efferth T (2013) Integration of different “-omics” technologies identifies inhibition of the IGF1R-Akt-mTOR signaling cascade involved in the cytotoxic effect of shikonin against leukemia cells.Evidence-based Complement Altern Med, 2013:818709 Link

2012

Wiench B, Eichhorn T, Paulsen M and Efferth T (2012) Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cells.Evidence-based Complement Altern Med, 2012:726025 Link

Wiench B, Eichhorn T, Korn B, Paulsen M and Efferth T (2012) Utilizing inherent fluorescence of therapeutics to analyze real-time uptake and multi-parametric effector kinetics.Methods, 57:376–382 Link

2011

Paulsen M*, Legewie S*, Eils R, Karaulanov E and Niehrs C (2011) Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development. Proc Natl Acad Sci USA, 108:10202–10207 (Editors' Choice in Science 333, 138). (*indicates joint contribution) Link

2018

Gruber L, Abdelfatah S, Fröhlich T, Reiter C, Klein V, Tsogoeva SB and Efferth T. (2018). Treatment of multidrug-resistant leukemia cells by novel artemisinin-, egonol-, and thymoquinone-derived hybrid compounds. Molecules, 28: 841.

Heidelberger JB, Voigt A, Borisova ME, Petrosino G, Ruf S, Wagner SA and Beli P. (2018). Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function. EMBO Rep, 19: e44754.

Mbaveng AT, Manekengb HT, Nguenangb GS, Dzotamb JK, Kuete V and Efferth T (2018). Cytotoxicity of 18 Cameroonian medicinal plants against drug sensitive and multi-factorial drug resistant cancer cells. J Ethnopharmacology, 222: 21–33.

Mbaveng AT, Ndontsac BL, Kuete V, Nguekeuc YMM, Çelikd I, Mbouangouerec R, Tanec P and Efferth T. (2018). A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death. Phytomedicine, 43: 78–85.

Özenver N, Saeed M, Ömur Demirezer L and Efferth T. (2018). Aloe-emodin as drug candidate for cancer therapy. Oncotarget, 9: 17770–17796

Roovers EF, Kaaij LJT, Redl S, Bronkhorst AW, Wiebrands K, de Jesus Domingues AM, Huang HY, Han CT, Riemer S, Dosch R, Salvenmoser W, Grün D, Butter F, van Oudenaarden A and Ketting RF. (2018). Tdrd6a regulates the aggregation of buc into functional subcellular compartments that drive germ cell specification. Dev Cell, 46: 285–301.e9.

Wanke F, Tang Y, Gronke K, Klebow S, Moos S, Hauptmann J, Shanmugavadivu A, Regen T, Mufazalov IA, Gabriel LA, Reißig S, Diefenbach A, Kurschus FC and Waisman A. (2018). Expression of IL-17F is associated with non-pathogenic Th17 cells. J Mol Med, 96: 819–829.

2017

Van Acker A, Gronke K, Biswas A, Martens L, Saeys Y, Filtjens J, Taveirne S, Van Ammel E, Kerre T, Matthys P, Taghon T, Vandekerckhove B, Plum J, Dunay IR, Diefenbach A and Leclercq G. (2017). A murine intestinal intraepithelial NKp46-negative innate lymphoid cell population characterized by group 1 properties. Cell Rep, 19: 1431–1443.

Dzama MM, Nigmatullina L, Sayols S, Kreim N and Soshnikova N. (2017). Distinct populations of embryonic epithelial progenitors generate Lgr5+ intestinal stem cells. Dev Biol, 432: 258–264.

Kazakevych J, Sayols S, Messner B, Krienke C and Soshnikova N. (2017). Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cells. Nucleic Acids Res, 45: 5770–5784.

Kuete V, Mbaveng AT, Sandjo LP, Zeino M and Efferth T. (2017). Cytotoxicity and mode of action of a naturally occurring naphthoquinone, 2-Acetyl-7-methoxynaphtho[2,3-B]furan-4,9-quinone towards multi-factorial drug-resistant cancer cells. Phytomedicine, 33: 62–68.

Nigmatullina L, Norkin M, Dzama MM, Messner B, Sayols S and Soshnikova N. (2017).  Id2 controls specification of Lgr5(+) intestinal stem cell progenitors during gut development. EMBO J, 36: 869–885.

2016

Kaymak A and Richly H. (2016). Zrf1 controls mesoderm lineage genes and cardiomyocyte differentiation. Cell Cycle, 15: 3306–3317.

Pataskar A, Jung J, Smialowski P, Noack F, Calegari F, Straub T and Tiwari VK. (2016). NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program. EMBO J, 35: 24-45

2015

Kirmes I, Szczurek A, Prakash K, Charapitsa I, Heiser C, Musheev M, Schock F, Fornalczyk K, Ma D, Birk U, Cremer C and Reid G. (2015). A transient ischemic environment induces reversible compaction of chromatin. Genome Biology, 16: 246.

Krieg B, Hirsch M, Scholz E, Nuhn L, Tabujew I, Bauer H, Decker S, Khobta A, Schmidt M, Tremel W, Zentel R, Peneva K, Koynov K, Mason AJ and Helm M. (2015). New techniques to assess in vitro release of siRNA from nanoscale polyplexes. Pharm Res, 32: 1957-74.

Sahu SK, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, Ortega F, Schmarowski N, Berninger B, Nitsch R, Schmidt M and Tiwari V. (2015). JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J, 34: 2162-2181.

Sakry D, Yigit H, Dimou L and Trotter J. (2015). Oligodendrocyte precursor cells synthesize neuromodulatory factors. PLoS One, 10: e0127222.

Stangenberg R, Wu Y, Hedrich J, Kurzbach D, Wehner D, Weidinger G, Kuan SL, Jansen MI, Jelezko F, Luh-mann HJ, Hinderberger D, Weil T and Müllen K. (2015). A polyphylene dendrimer drug transporter with precisely positioned amphiphilic surface patches. Adv Healthc Mater, 4: 377-84.

Wu CF and Efferth T. (2015). Miltirone induces G2/M cell cycle arrest and apoptosis in CCRF-CEM acute lymphoblastic leukemia cells. J Nat Prod, 78: 1339-1347.

Zeino M, Brenk R, Gruber L, Zehl M, Urban E, Kopp B and Efferth T. (2015). Cytotoxicity of cardiotonic steroids in sensitive and multi-drug resistant leukemia cells and the link with Na+/K+-ATPase. J Steroid Biochem, 150: 97-111.

2014

Hamm R, Zeino M, Frewert S and Efferth T. (2014). Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B. Toxicol Appl Pharmacol, 281: 78-86.

Hamm R, Chen YR, Seo EJ, Zeino M, Wu CF, Müller R, Yang NS and Efferth T. (2014). Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells. Biochemical Pharmacol, 91: 18-30.