Prof. Geneviève Almouzni

Institut Curie, PSL University, Sorbonne Universités, UPMC University, CNRS, UMR3664, Paris, France

Geneviève Almouzni is Director of the research center at the Institut Curie in Paris, France. She investigates how chromatin organization is established, propagated, maintained and changed during development and in response to environmental cues. In particular, she dissects the mechanisms behind chromatin assembly, characterizing the key chaperones involved in nucleosome assembly and defining the dynamics of new histone incorporation in chromatin

Prof. Peter Becker (Chair)

Biomedical Center Munich, Ludwig Maximilian University Munich, Germany

Peter Becker is Acting Director of the Biomedical Center Munich and heads the Molecular Biology Division. His research focusses on understanding the dynamics of chromatin organisation and its influence on gene expression and DNA repair. In particular, his group is interested in the physiological roles and mechanism of action of nucleosome remodelling factors, and in understanding the chromosome-wide gene regulation that underlies dosage compensation in Drosophila.

Prof. Bradley Cairns

Huntsman Cancer Institute, University of Utah, Salt Lake City, USA

Professor Bradley Cairns is an HHMI investigator at the Huntsman Cancer Institute. He investigates how chromatin structure helps regulate gene transcription. To do this he characterises the large protein complexes that are responsible for remodeling and modifying chromosomal structure, and studies how these chromatin-regulatory complexes function in living cells. He also studies how chromatin structure and DNA methylation contribute to pluripotency in germ cells and early embryos.

Prof. Ian Hickson

Center for Chromosome Stability and Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Denmark

Ian Hickson is the Director of the DNRF Center for Chromosome Stability, Theme Leader in the Center for Healthy Aging and a Professor of Molecular Aging in the Department of Cellular and Molecular Medicine at the University of Copenhagen, Denmark. He is a leading expert in DNA repair factors in eukaryotic cells, and his lab studies how these factors act to maintain genome stability. He is particularly interested in genes which when mutated lead to defective genome maintenance, causing genetic disorders of premature ageing, cancer, neurodegeneration or infertility.

Prof. Rudolf Jaenisch

The Whitehead Institute for Biomedical Research, Cambridge, USA

Rudolf Jaenisch is Professor of Biology at the Whitehead Institute and the Department of Biology, MIT. He generated the first transgenic mice carrying exogenous DNA in the germ line and was the first to use insertional mutagenesis to identify developmental genes. He has defined molecular mechanisms that are crucial for nuclear reprogramming and most recently has used direct reprogramming of somatic cells to generate “induced Pluripotent Stem” (iPS) cells.

Prof. Ruth Lehmann

The Whitehead Institute for Biomedical Research, Cambridge, USA

Ruth Lehmann is an HHMI Investigator, the president and director of the Whitehead Institute, and Professor of Biology at MIT. Her lab focusses on the development of the Drosophila germ line. She is particularly interested in understanding the role of RNA localisation and translation in germ cell specification and fate decisions. Additionally, her group is currently studying the migration of primordial germ cells, as well as investigating mechanisms that protect the genome from damage in the germ line.

Dr Jan-Michael Peters

Research Institute of Molecular Pathology (IMP), Vienna, Austria

Dr Jan-Michael Peters is Scientific Director of the Research Institute of Molecular Pathology (IMP) in Vienna. His research into mitosis and chromatin biology has led to the discovery of several proteins with important roles in cell division. In particular, he is interested in understanding how sister chromatid cohesion is regulated in cells at a molecular level. Dr Peters is currently leading the MitoSys project, an international, interdisciplinary consortium, which aims to build a comprehensive model of mitosis using a systems biology approach. He participates in the SAB as a permanent guest without a vote.

Previous SAB members

Prof. Ingrid Grummt (2011 - 2014)

German Cancer Research Center (DKFZ), Heidelberg, Germany

Prof. Josef Jiricny (2011 - 2021)

Institute of Molecular Cancer Research, University of Zurich, Switzerland

Prof. Jorg Michaelis (2011 - 2014)

University Medical Center, Mainz, Germany

Prof. Renato Paro (Chair 2011 - 2017)

Swiss Federal Institute of Technology, Basel, Switzerland

Prof. Ernst-Ludwig Winnacker (2011 - 2014)

International Human Frontier Science Program Organization, Strasbourg, France