Proteome Organisation & Dynamics

Anton Khmelinskii

Positions held

  • Since 2018: Group Leader, Institute of Molecular Biology (IMB), Mainz
  • 2010–2017: Postdoctoral Researcher, Center for Molecular Biology (ZMBH), Heidelberg University; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto; European Molecular Biology Laboratory (EMBL), Heidelberg

Education

  • 2010: PhD in Biology, University of Heidelberg
  • 2005: Licenciatura degree in Biochemistry, University of Lisbon

Recent publications by Anton Khmelinskii

Kowalski L, Bragoszewski P, Khmelinskii A, Glow E, Knop M and Chacinska A (2018). Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins. BMC Biol, 16, 66

Kats I, Khmelinskii A, Kschonsak M, Huber F, Knieß RA, Bartosik A and Knop M (2018). Mapping degradation signals and pathways in a eukaryotic N-terminome. Mol Cell, 70, 488-501

Meurer M, Duan Y, Sass E, Kats I, Herbst K, Buchmuller BC, Dederer V, Huber F, Kirrmaier D, Štefl M, Van Laer K, Dick TP, Lemberg MK, Khmelinskii A#, Levy ED# and Knop M#. (2018). Genome-wide C-SWAT library for high-throughput yeast genome tagging. Nat Methods, 15: 598–600. (# indicates joint correspondence)

Bunina D, Štefl M, Huber F, Khmelinskii A, Meurer M, Barry JD, Kats I, Kirrmaier D, Huber W and Knop M. (2017).  Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities. Nucleic Acids Res, 45, 11144–11158.

Caydasi AK, Khmelinskii A, Duenas-Sanchez R, Kurtulmus B, Knop M and Pereira G (2017). Temporal and compartment-specific signals co-ordinate mitotic exit with spindle position. Nat Commun, 8, 14129

Huber F, Bunina D, Gupta I, Khmelinskii A, Meurer M, Theer P, Steinmetz LM and Knop M (2016). Protein abundance control by non-coding antisense transcription. Cell Reports, 15, 2625-36

Yofe I#, Weill U, Meurer M, Chuartzman S#, Zalckvar E, Goldman O, Ben-Dor S, Schütze C, Wiedemann N, Knop M, Khmelinskii A# and Schuldiner M# (2016). One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy. Nature Methods, 13, 371-8 (# joint corresponding authors)

Khmelinskii A*, Blaszczak E*, Pantazopoulou M, Fischer B, Omnus DJ, Le Dez G, Brossard A, Gunnarsson A, Barry JD, Meurer M, Kirrmaier D, Boone C, Huber W, Rabut G, Ljungdahl PO and Knop M (2014). Protein quality control at the inner nuclear membrane. Nature, 516, 410-3 (* joint first authors)


Research website