Biology of Non-coding RNA

Positions held

  • 2015-2017: Executive Director, IMB, Mainz
  • Since 2012: Scientific Director, Institute of Molecular Biology (IMB), Mainz;
    Professor, Faculty of Biology, University of Mainz
  • Since 2010: Professor of Epigenetics in Development, University of Utrecht
  • 2005-2012: Group Leader, Hubrecht Institute, Utrecht
  • 2000-2004: Postdoctoral Researcher, Hubrecht Laboratory, Utrecht
  • 2000: Postdoctoral Researcher, Cold Spring Harbor Laboratories


  • 2000: PhD in Molecular Biology, Netherlands Cancer Institute, Amsterdam
  • 1994: Masters in Chemistry, University of Leiden

Recent publications publications by René Ketting

Almeida MV, Dietz S, Redl S, Karaulanov E, Hildebrandt A, Renz C, Ulrich HD, König J, Butter F, Ketting RF (2018). GTSF-1 is required for formation of a functional RNA-dependent RNA Polymerase complex in Caenorhabditis elegans. EMBO J, 37(12). pii: e99325

Bronkhorst AW, Ketting RF (2018). Trimming it short: PNLDC1 is required for piRNA maturation during mouse spermatogenesis. EMBO Rep, 19(3). pii: e45824

Roovers EF, Kaaij LJT, Redl S, Bronkhorst AW, Wiebrands K, de Jesus Domingues AM, Huang HY, Han CT, Riemer S, Dosch R, Salvenmoser W, Grün D, Butter F, van Oudenaarden A and Ketting RF (2018). Tdrd6a regulates the aggregation of Buc into functional subcellular compartments that drive germ cell specification. Dev Cell, 46: 285–301.e9

Lebedeva S, de Jesus Domingues AM, Butter F, Ketting RF (2017). Characterization of genetic loss-of-function of Fus in zebrafish. RNA Biol, 14, 29-35

Kaaij LJ, Mokry M, Zhou M, Musheev M, Geeven G, Melquiond AS, de Jesus Domingues AM, de Laat W, Niehrs C, Smith AD, Ketting RF (2016). Enhancers reside in a unique epigenetic environment during early zebrafish development. Genome Biology, 17(1):146

Research website