Old proteins - new functions: non-classical roles and gene regulation of globins in mammals

Thomas Hankeln

Positions held

  • Since 2001: Professor (Molecular Genetics), Faculty of Biology, JGU, Mainz
  • 1994-2001: Working Group Leader, Institute of Molecular Genetics, JGU, Mainz
  • 1990-1993: Postdoc, Institute of Genetics, JGU, Mainz

Education

  • 1990: PhD at Ruhr-University Bochum
  • 1985: Diploma in Biology, Ruhr-University Bochum

Most relevant publications by Thomas Hankeln

Bicker A, Brahmer AM, Meller S, Kristiansen G, Gorr TA and Hankeln T (2015). The Distinct Gene Regulatory Network of Myoglobin in Prostate and Breast Cancer. PLoS One, 10, e0142662

Burmester T and Hankeln T (2014). Function and evolution of vertebrate globins. Acta Physiol (Oxf). 211, 501-514  

Bicker A, Dietrich D, Gleixner E, Kristiansen G, Gorr TA and Hankeln T (2014). Extensive transcriptional complexity during hypoxia-regulated expression of the myoglobin gene in cancer. Hum Mol Genet, 23, 479-490

Hoogewijs D, Ebner B, Germani F, Hoffmann FG, Fabrizius A, Moens L, Burmester T, Dewilde S, Storz JF, Vinogradov SN and Hankeln T (2012). Androglobin: a chimeric globin in metazoans that is preferentially expressed in Mammalian testes. Mol Biol Evol, 29, 1105-1114  

Avivi A, Gerlach F, Joel A, Reuss S, Burmester T, Nevo E and Hankeln T (2010). Neuroglobin, cytoglobin, and myoglobin contribute to hypoxia adaptation of the subterranean mole rat Spalax. Proc Natl Acad Sci U S A107, 21570-21575

Hankeln T, Jaenicke V, Kiger L, Dewilde S, Ungerechts G, Schmidt M, Urban J, Marden MC, Moens L and Burmester T (2002). Characterization of Drosophila hemoglobin. Evidence for hemoglobin-mediated respiration in insects. J Biol Chem, 277, 29012-29017

Burmester T, Weich B, Reinhardt S and Hankeln T (2000). A vertebrate globin expressed in the brain. Nature, 28, 407, 520-523

 

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