Primary cilia and miRNA

Research website

Positions held

Since 2015: Junior Professor, Institute of Molecular Physiology, Johannes Gutenberg University, Mainz
2012-2014: Research Fellow, National Eye Institute, National Institute of Health
2008-2011: Postdoctoral Fellow, National Institute of Deafness and Communication Disorders, National Institute of Health

Education

2003-2008: University College London, UK, PhD - Mutational and Functional Analyses of Bardet-Biedl syndrome
2003: University of Bath, UK, Master of Biochemistry (MBiochem) (II-I)

Selected publications by Helen May-Simera

Patnaik SR, Kretschmer V, Brücker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL (2019) Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci, 76(4):757-775 Link

May-Simera HL, Wan Q, Jha BS, Hartford J, Khristov V, Dejene R, Chang J, Patnaik S, Lu Q, Banerjee P, Silver J, Insinna-Kettenhofen C, Patel D, Lotfi M, Malicdan M, Hotaling N, Maminishkis A, Sridharan R, Brooks B, Miyagishima K, Gunay-Aygun M, Pal R, Westlake C, Miller S, Sharma R, Bharti K (2018) Primary Cilium-Mediated Retinal Pigment Epithelium Maturation Is Disrupted in Ciliopathy Patient Cells. Cell Rep, 22(1):189-205 Link

May-Simera HL, Gumerson JD, Gao C, Campos M, Cologna SM, Beyer T, Boldt K, Kaya KD, Patel N, Kretschmer F, Kelley MW, Petralia RS, Davey MG, Li T (2016) Loss of MACF1 Abolishes Ciliogenesis and Disrupts Apicobasal Polarity Establishment in the Retina. Cell Rep, 17(5):1399-1413 Link

May-Simera HL, Petralia RS, Montcouquiol M, Wang YX, Szarama KB, Liu Y, Lin W, Deans MR, Pazour GJ, Kelley MW (2015) Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea. Development, 142(3):555-66 Link