Genomic views of protein-RNA interactions and splicing regulation

Positions held

  • Since 2013: Group Leader, Institute of Molecular Biology (IMB), Mainz
  • 2008-2013: Postdoctoral Researcher, MRC Laboratory of Molecular Biology, Cambridge

Education

  • 2008: PhD in Biology, Phillip University, Marburg
  • 2003: Diploma in Biology, Ludwig Maximilian University, Munich

Recent publications by Julian König

Buchbender A, Mutter H, FX Sutandy R, Körtel N, Hänel H, Busch A, Ebersberger S and König J (2019) Improved library preparation with the new iCLIP2 protocol. Methods, doi:10.1016/j.ymeth.2019.10.003

Dold A, Han H, Liu N, Hildebrandt A, Brüggemann M, Rücklé C, Busch A, Beli P, Zarnack K, König J, Roignant JY and Lasko P (2019) Makorin 1 controls embryonic patterning by alleviating Bruno-mediated repression of oskar translation. bioRxiv, doi: 10.1101/501643

Almeida MV, Dietz S, Redl S, Karaulanov E, Hildebrandt A, Renz C, Ulrich HD, König J, Butter F, Ketting RF (2018). GTSF-1 is required for formation of a functional RNA-dependent RNA Polymerase complex in Caenorhabditis elegans. EMBO J, 37(12). pii: e99325

Sutandy FXR, Ebersberger S, Huang L, Busch A, Bach M, Kang HS, Fallmann J, Maticzka D, Backofen R, Stadler PF, Zarnack K, Sattler M, Legewie S#, König J# (2018). In vitro iCLIP-based modeling uncovers how the splicing factor U2AF2 relies on regulation by cofactors. Genome Res, 28(5):699-713 (#indicates joint correspondence)

Hildebrandt A, Alanis-Lobato G, Zarnack K, Andrade-Navarro MA, Beli P# and König J# (2017). The interaction profile of RNA-binding ubiquitin ligases reveals a link between posttranscriptional regulation and the ubiquitin system. Sci Rep, 7(1):16582 (#indicates joint correspondence)

Attig J, Mozos I, Haberman N, Wang Z, Emmett W, Zarnack K, König J# and Ule J# (2016). Splicing repression allows the gradual emergence of new Alu-exons in primate evolution. eLife, 5, e19545 (#indicates joint correspondence)

Sutandy FX*, Hildebrandt A* and König J (2016). Profiling the binding sites of RNA-binding proteins with nucleotide resolution using iCLIP. Methods Mol Biol, 1358, 175-195 (*indicates joint contribution)

Coelho MB, Attig J, Bellora N, König J, Hallegger M, Kayikci M, Eyras E, Ule J and Smith CW (2015). Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB. EMBO J, 34, 653-668

Research website