Cremer
Research Publications2026
Zhu X*, Chetty VK*, Ghanam J, Hila A, Yang Q, Strickfaden H, Bonn M, Cremer C, Hoyer PF, Liu X and Thakur BK (2026) Single-molecule localization microscopy imaging of extracellular vesicle DNA in recipient cells. J Transl Med, doi: 10.1186/s12967-025-07563-3 (*indicates joint contribution) Link
2025
Karimian T, Cremer C, Weghuber J and Schneckenburger H (2025) Cell aging - a relevant factor in live cell microscopy (mini-review). Prog Biophys Mol Biol, 198:61-70 Link
2024
Gelleri M, Sterr M, Strickfaden H, Cremer C, Cremer T and Cremer M (2024) Perspective Article: Space-time dynamics of genome replication studied withsuper-resolved microscopy. Postepy Biochem, 70:8-21 Link
Zhu X, Chen Q, Zhao H, Yang Q, Goudappagouda, Gelléri M, Ritz S, Ng D, Koynov K, Parekh SH, Chetty VK, Thakur BK, Cremer C, Landfester K, Müllen K, Terenzio M, Bonn M, Narita A and Liu X (2024) Intrinsic burst-blinking nanographenes for super-resolution bioimaging. J Am Chem Soc, 146:5195-5203 Link
2023
Chapman KB*, Filipsky F*, Peschke N, Gelléri M, Weinhardt V, Braun A, Hausmann M° and Cremer C° (2023) A comprehensive method to study the DNA's association with lamin and chromatin compaction in intact cell nuclei at super resolution. Nanoscale, 15:742-756 (*indicates joint contribution, °indicates joint senior author) Link
Gelléri M*,#, Chen SY*, Hübner B, Neumann J, Kröger O, Sadlo F, Imhoff J, Hendzel MJ, Cremer M, Cremer T, Strickfaden H# and Cremer C# (2023) True-to-scale DNA-density maps correlate with major accessibility differences between active and inactive chromatin. Cell Rep, 42:112567 (*indicates joint contribution, #indicates joint correspondence) Link
Ghanam J*, Chetty VK*, Zhu X, Liu X, Gelléri M, Barthel L, Reinhardt D, Cremer C# and Thakur BK# (2023) Single molecule localization microscopy for studying small extracellular vesicles. Small, 19:e2205030 (*indicates joint contribution, #indicates joint correspondence) Link
2022
Chetty VK, Ghanam J, Anchan S, Reinhardt K, Brenzel A, Gelléri M, Cremer C, Grueso-Navarro E, Schneider M, von Neuhoff N, Reinhardt D, Jablonska J, Nazarenko I and Thakur BK (2022) Efficient small extracellular vesicles (EV) isolation method and evaluation of EV-associated DNA role in cell-cell communication in cancer. Cancers, 14:2068 Link
Cremer C and Birk U (2022) Spatially modulated illumination microscopy: application perspectives in nuclear nanostructure analysis. Philos Trans R Soc A Math Phys Eng Sci, 380:20210152 Link
Rose R, Peschke N, Nigi E, Gelléri M, Ritz S, Cremer C, Luhmann HJ and Sinning A (2022) Chromatin compaction precedes apoptosis in developing neurons. Commun Biol, 5:797 Link
2021
Lang F*, Contreras-Gerenas MF*, Gelléri M, Neumann J, Kröger O, Sadlo F, Berniak K, Marx A, Cremer C#, Wagenknecht HA# and Allgayer H# (2021) Tackling tumour cell heterogeneity at the super-resolution level in human colorectal cancer tissue. Cancers, 13:3692 (*indicates joint contribution, #indicates joint correspondence) Link
2020
Cremer T#, Cremer M, Hübner B, Silahtaroglu A, Hendzel M, Lanctôt C, Strickfaden H# and Cremer C# (2020) The Interchromatin Compartment Participates in the Structural and Functional Organization of the Cell Nucleus. BioEssays, 42:1900132 (#indicates joint correspondance) Link
Schneckenburger H, Richter V, Gelleri M, Ritz S, Vaz Pandolfo R, Schock F, Hase VJ, Birk U and Cremer C (2020) High-resolution deep view microscopy of cells and tissues. Quantum Electron, 50:2–8 Link
2019
Chen SY, Heintzmann R and Cremer C (2019) Sample drift estimation method based on speckle patterns formed by backscattered laser light. Biomed Opt Express, 10:6462–6475 Link
Kordon MM, Szczurek A, Berniak K, Szelest O, Solarczyk K, Tworzydło M, Wachsmann-Hogiu S, Vaahtokari A, Cremer C, Pederson T and Dobrucki JW (2019) PML-like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication-based single-strand breaks. FASEB J, 33:2301–2313 Link
Lee JH, Laure Djikimi Tchetgna F, Krufczik M, Schmitt E, Cremer C, Estvater FB and Hausmann M (2018) COMBO-FISH: A versatile tool beyond standard FISH to study chromatin organization by fluorescence light microscopy. OBM Genet, 3:1–28 Link
Liu X*, Chen SY*, Chen Q, Yao X, Gelléri M, Ritz S, Kumar S, Cremer C, Landfester K, Müllen K, Parekh S, Narita A and Bonn M (2019) Nanographenes: Ultrastable, switchable, and bright probes for super-resolution microscopy. Angew Chemie Int Ed, 59:496–502 (*indicates joint contribution) Link
Neumann J, Ziegler K, Gelléri M, Fröhlich-Nowoisky J, Liu F, Bellinghausen I, Schuppan D, Birk U, Pöschl U, Cremer C and Lucas K (2019) Nanoscale distribution of TLR4 on primary human macrophages stimulated with LPS and ATI. Nanoscale, 11:9769–9779 Link
Ziegler K, Neumann J, Liu F, Fröhlich-Nowoisky J, Cremer C, Saloga J, Reinmuth-Selzle K, Pöschl U, Schuppan D, Bellinghausen I and Lucas K (2019) Nitration of wheat amylase trypsin inhibitors increases their innate and adaptive immunostimulatory potential in vitro. Front Immunol, 9:3174 Link
2018
Chen S-Y, Bestvater F, Schaufler W, Heintzmann R and Cremer C (2018) Patterned illumination single molecule localization microscopy (piSMLM): User defined blinking regions of interest. Opt Express, 26:30009–30020 Link
Cremer C (2018) Mobilität und dynamik im Zellkern. Heidelb Jahrb, 3:157–192 Link
Cremer C (2018) Mit Laserlicht ins innerste des Zellkerns. Pages 43–91 in: Heidelberger Physiker berichten (eds. Appenzeller I, Dubbers D, Siebig H & Winnacker A), Physikalisches Institut, Heidelberg
Cremer C, Szczurek A, Strickfaden H, Birk U, Cremer M and Cremer T (2018) Der Zellkern - eine Stadt in der Zelle, Teil 2. Biol unserer Zeit, 48:45–53 Link
Cremer T, Cremer M and Cremer C (2018) The 4D nucleome: Genome compartmentalization in an evolutionary context. Biochem, 83:313–325 Link
Eryilmaz M, Schmitt E, Krufczik M, Theda F, Lee J-H, Cremer C, Bestvater F, Schaufler W, Hausmann M and Hildenbrand G (2018) Localization microscopy analyses of MRE11 clusters in 3D-conserved cell nuclei of different cell lines. Cancers, 10:25 Link
Schink A, Neumann J, Leifke AL, Ziegler K, Fröhlich-Nowoisky J, Cremer C, Thines E, Weber B, Pöschl U, Schuppan D and Lucas K (2018) Screening of herbal extracts for TLR2- and TLR4-dependent anti-inflammatory effects.PLOS One, 13:e0203907 Link
Szczurek A, Birk U, Knecht H, Dobrucki J, Mai S and Cremer C (2018) Super-resolution binding activated localization microscopy through reversible change of DNA conformation. Nucleus, 9:182–189 Link
2017
Bach M, Savini C, Krufczik M, Cremer C, Rösl F and Hausmann M (2017) Super-resolution localization microscopy of γ-H2AX and heterochromatin after folate deficiency.Int J Mol Sci, 18:1726 Link
Birk U, Szczurek A and Cremer C (2017) Super-resolved linear fluorescence localization microscopy using photostable fluorophores: A virtual microscopy study. Opt Commun, 404:42–50 Link
Birk U, Von Hase J and Cremer C (2017) Super-resolution microscopy with very large working distance by means of distributed aperture illumination.Sci Rep, 7:3685 Link
Cremer C, Szczurek A, Schock F, Gourram A and Birk U (2017) Super-resolution microscopy approaches to nuclear nanostructure imaging. Methods, 123:11–32 Link
Hausmann M, Ilić N, Pilarczyk G, Lee J-H, Logeswaran A, Borroni AP, Krufczik M, Theda F, Waltrich N, Bestvater F, Hildenbrand G, Cremer C and Blank M (2017) Challenges for super-resolution localization microscopy and biomolecular fluorescent nano-probing in cancer research.Int J Mol Sci, 18:2066 Link
Richter V, Bruns S, Bruns T, Weber P, Wagner M, Cremer C and Schneckenburger H (2017) Axial tomography in live cell laser microscopy. J Biomed Opt, 22:91505 Link
Szczurek A, Klewes L, Xing J, Gourram A, Birk U, Knecht H, Dobrucki JW, Mai S and Cremer C (2017) Imaging chromatin nanostructure with binding-activated localization microscopy based on DNA structure fluctuations.Nucleic Acids Res, 45:e56 Link
2016
Boyd PS, Struve N, Bach M, Eberle JP, Gote M, Schock F, Cremer C, Kriegs M and Hausmann M (2016) Clustered localization of EGFRvIII in glioblastoma cells as detected by high precision localization microscopy. Nanoscale, 8:20037–20047 Link
Cremer C and Birk U (2016) Perspectives in super-resolved fluorescence microscopy: What comes next?Front Phys, 4:11 Link
Moser F, Hildenbrand G, Müller P, Al Saroori A, Biswas A, Bach M, Wenz F, Cremer C, Burger N, Veldwijk MR and Hausmann M (2016) Cellular uptake of gold nanoparticles and their behavior as labels for localization microscopy. Biophys J, 110:947–953 Link
Neumann J, Scherhag A, Otten S, Shen F, Leifke AL, Birk U, Greb C, Lucas K and Cremer C (2016) Chronic inflammation under the microscope. Micros Today, 24:38–45 Link
Perez RL, Best G, Nicolay NH, Greubel C, Rossberger S, Reindl J, Dollinger G, Weber KJ, Cremer C and Huber PE (2016) Superresolution light microscopy shows nanostructure of carbon ion radiation-induced DNA double-strand break repair foci. FASEB J, 30:2767–2776 Link
Pierzyńska-Mach A, Szczurek A, Cella Zanacchi F, Pennacchietti F, Drukała J, Diaspro A, Cremer C, Darzynkiewicz Z and Dobrucki JW (2016) Subnuclear localization, rates and effectiveness of UVC-induced unscheduled DNA synthesis visualized by fluorescence widefield, confocal and super-resolution microscopy. Cell Cycle, 15:1156–1167 Link
Szczurek A, Xing J, Birk UJ and Cremer C (2016) Single molecule localization microscopy of mammalian cell nuclei on the nanoscale. Front Genet, 7:114 Link
Żurek-Biesiada D, Szczurek AT, Prakash K, Best G, Mohana GK, Lee H-K, Roignant J-Y, Dobrucki JW, Cremer C and Birk U (2016) Quantitative super-resolution localization microscopy of DNA in situ using Vybrant®DyeCycleTM Violet fluorescent probe.Data Br, 7:157–171 Link
Zurek-Biesiada D, Szczurek AT, Prakash K, Mohana GK, Lee HK, Roignant JY, Birk UJ, Dobrucki JW and Cremer C (2016) Localization microscopy of DNA in situ using Vybrant® DyeCycleTM Violet fluorescent probe: A new approach to study nuclear nanostructure at single molecule resolution. Exp Cell Res, 343:97–106 Link
2015
Cremer T, Cremer M, Hübner B, Strickfaden H, Smeets D, Popken J, Sterr M, Markaki Y, Rippe K and Cremer C (2015) The 4D nucleome: Evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments. FEBS Lett, 589:2931–2943 Link
Grab AL, Hagmann M, Dahint R and Cremer C (2015) Localization microscopy (SPDM) facilitates high precision control of lithographically produced nanostructures. Micron, 68:1–7 Link
Kirmes I, Szczurek A, Prakash K, Charapitsa I, Heiser C, Musheev M, Schock F, Fornalczyk K, Ma D, Birk U, Cremer C and Reid G (2015) A transient ischemic environment induces reversible compaction of chromatin. Genome Biol, 16:246 Link
Oleksiuk O, Abba M, Tezcan KC, Schaufler W, Bestvater F, Patil N, Birk U, Hafner M, Altevogt P, Cremer C and Allgayer H (2015) Single-molecule localization microscopy allows for the analysis of cancer metastasis-specific miRNA distribution on the nanoscale. Oncotarget, 6:44745–44757 Link
Prakash K, Fournier D, Redl S, Best G, Borsos M, Tiwari VK, Tachibana-Konwalski K, Ketting RF, Parekh SH, Cremer C and Birk UJ (2015) Superresolution imaging reveals structurally distinct periodic patterns of chromatin along pachytene chromosomes. Proc Natl Acad Sci USA, 112:14635–14640 Link
Stuhlmüller M, Schwarz-Finsterle J, Fey E, Lux J, Bach M, Cremer C, Hinderhofer K, Hausmann M and Hildenbrand G (2015) In situ optical sequencing and structure analysis of a trinucleotide repeat genome region by localization microscopy after specific COMBO-FISH nano-probing. Nanoscale, 7:17938–17946 Link
2014
Cremer C (2014) Far-field Light Microscopy. Pages 1–13 in: eLS John Wiley & Sons, Ltd, Chichester Link
Cremer C, Kaufmann R, Gunkel M, Polanski F, Müller P, Dierkes R, Degenhard S, Wege C, Hausmann M and Birk U (2014) Application perspectives of localization microscopy in virology. Histochem Cell Biol, 142:43–59 Link
Cremer T, Cremer C and Lichter P (2014) Recollections of a scientific journey published in human genetics: From chromosome territories to interphase cytogenetics and comparative genome hybridization. Hum Genet, 133:403–416 Link
Müller P, Lemmermann NA, Kaufmann R, Gunkel M, Paech D, Hildenbrand G, Holtappels R, Cremer C and Hausmann M (2014) Spatial distribution and structural arrangement of a murine cytomegalovirus glycoprotein detected by SPDM localization microscopy. Histochem Cell Biol, 142:61–67 Link
Szczurek AT, Prakash K, Lee H-K, Żurek-Biesiada DJ, Best G, Hagmann M, Dobrucki JW, Cremer C and Birk U (2014) Single molecule localization microscopy of the distribution of chromatin using Hoechst and DAPI fluorescent probes. Nucleus, 5:331–340 Link
Wang Q, Dierkes R, Kaufmann R and Cremer C (2014) Quantitative analysis of individual hepatocyte growth factor receptor clusters in influenza A virus infected human epithelial cells using localization microscopy. Biochim Biophys Acta - Biomembr, 1838:1191–1198 Link
2013
Best G, Amberger R and Cremer C (2013) Super-resolution microscopy: Interference and pattern techniques. Pages 345–374 in: Fluorescence Microscopy: From principles to biological applications (ed. Kubitscheck U), Wiley‐VCH Verlag, Weinheim Link
Cremer C and Masters BR (2013) Resolution enhancement techniques in microscopy. Eur Phys J H, 38:281–344 Link
Hausmann M, Müller P, Kaufmann R and Cremer C (2013) Entering the nano-cosmos of the cell by means of spatial position determination microscopy (SPDM): Implications for medical diagnostics and radiation research. Pages 93–95 in: International Symposium on Biomedical Engineering and Medical Physics, 10-12 October, 2012, Riga, Latvia. IFMBE Proceedings, vol 38 (eds. Dekhtyar Y, Katashev A & Lancere L), Springer, Berlin, Heidelberg Link
Rossberger S, Ach T, Best G, Cremer C, Heintzmann R and Dithmar S (2013) High-resolution imaging of autofluorescent particles within drusen using structured illumination microscopy. Br J Ophthalmol, 97:518–523 Link
Rossberger S, Best G, Baddeley D, Heintzmann R, Birk U, Dithmar S and Cremer C (2013) Combination of structured illumination and single molecule localization microscopy in one setup. J Opt, 15:94003 Link
2012
Ach T, Best G, Rossberger S, Heintzmann R, Cremer C and Dithmar S (2012) Autofluorescence imaging of human RPE cell granules using structured illumination microscopy. Br J Ophthalmol, 96:1141–1144 Link
Cremer C (2012) Vom farbenkreis zum Supermikroskop: Goethe – dilettant oder fachmann? Pages 74–94 in: Bayerische Akademie der schönen Künste. Jahrbuch (ed. Küffe S), Wallstein Verlag, Göttingen Link
Cremer C (2012) Optics far beyond the diffraction limit. Pages 1359–1397 in: Springer Handbook of Lasers and Optics (ed. Träger F), Springer, Berlin & Heidelberg Link
Cremer T, Markaki Y, Hübner B, Zunhammer A, Strickfaden H, Beichmanis S, Heß M, Schermelleh L, Cremer M and Cremer C (2012) Chromosome territory organization within the nucleus. Pages 451–484 in: Reviews in Cell Biology and Molecular Medicine, Supplement 5 Epigenetic Regulation and Epigenomics (ed. Meyers RA), Wiley-VCH, Weinheim Link
Huber O, Brunner A, Maier P, Kaufmann R, Couraud P-O, Cremer C and Fricker G (2012) Localization microscopy (SPDM) reveals clustered formations of P-glycoprotein in a human blood-brain barrier model. PLOS One, 7:e44776 Link
Kaufmann R, Cremer C and Gall JG (2012) Superresolution imaging of transcription units on newt lampbrush chromosomes. Chromosom Res, 20:1009–1015 Link
Kaufmann R, Piontek J, Grüll F, Kirchgessner M, Rossa J, Wolburg H, Blasig IE and Cremer C (2012) Visualization and quantitative analysis of reconstituted tight junctions using localization microscopy. PLOS One, 7:e31128 Link
Maruyama EO, Hori T, Tanabe H, Kitamura H, Matsuda R, Tone S, Hozak P, Habermann FA, von Hase J, Cremer C, Fukagawa T and Harata M (2012) The actin family member Arp6 and the histone variant H2A.Z are required for spatial positioning of chromatin in chicken cell nuclei. J Cell Sci, 125:3739–3743 Link
Müller P, Weiland Y, Kaufmann R, Gunkel M, Hillebrandt S, Cremer C and Hausmann M (2012) Analysis of fluorescent nanostructures in biological systems by means of spectral position determination microscopy (SPDM). Pages 3–12 in: Current Microscopy Contributions to Advances in Science and Technology (ed. Méndez-Vilas A), Formatex, Badajoz Link
2011
Baddeley D, Crossman D, Rossberger S, Cheyne JE, Montgomery JM, Jayasinghe ID, Cremer C, Cannell MB and Soeller C (2011) 4D super-resolution microscopy with conventional fluorophores and single wavelength excitation in optically thick cells and tissues. PLOS One, 6:e20645 Link
Best G, Amberger R, Baddeley D, Ach T, Dithmar S, Heintzmann R and Cremer C (2011) Structured illumination microscopy of autofluorescent aggregations in human tissue. Micron, 42:330–335 Link
Brunner A, Best G, Amberger R, Lemmer P, Ach T, Dithmar S, Heintzmann R and Cremer C (2011) Fluorescence microscopy with structured excitation illumination. Pages 543–560 in: Handbook of Biomedical Optics (eds. Boas DA, Constantinos P & Ramanujam N), CRC Press, Boca Raton Link
Cremer C (2011) Mikroskope und Mikroben. Pages 99–136 in: Viren und andere Mikroben: Heil oder Plage? (ed. Sonntag K), Universitätsverlag Winter, Heidelberg Link
Cremer C (2011) Lichtmikroskopie unterhalb des Abbe-Limits. Lokalisationsmikroskopie. Phys unserer Zeit, 42:21–29 Link
Cremer C, Kaufmann R, Gunkel M, Pres S, Weiland Y, Müller P, Ruckelshausen T, Lemmer P, Geiger F, Degenhard S, Wege C, Lemmermann NAW, Holtappels R, Strickfaden H and Hausmann M (2011) Superresolution imaging of biological nanostructures by spectral precision distance microscopy. Biotechnol J, 6:1037–1051 Link
Hübschmann D, Kepper N, Cremer C and Kreth G (2011) Quantitative approaches to nuclear architecture analysis and modelling. Pages 87–129 in: Advances in nuclear architecture (eds. Adams NM & Freemont PS), Springer, Berlin & Heidelberg Link
Kaufmann R, Müller P, Hausmann M and Cremer C (2011) Imaging label-free intracellular structures by localisation microscopy. Micron, 42:348–352 Link
Kaufmann R, Müller P, Hildebrand G, Hausmann M and Cremer C (2011) Analysis of Her2/neu membrane protein clusters in different types of breast cancer cells using localization microscopy. J Microsc, 242:46–54 Link
Staier F, Eipel H, Matula P, Evsikov A V., Kozubek M, Cremer C and Hausmann M (2011) Micro axial tomography: A miniaturized, versatile stage device to overcome resolution anisotropy in fluorescence light microscopy. Rev Sci Instrum, 82:093701 Link
Weiland Y, Lemmer P and Cremer C (2011) Combining FISH with localisation microscopy: Super-resolution imaging of nuclear genome nanostructures. Chromosom Res, 19:5–23 Link
2010
Ach T, Best G, Ruppenstein M, Amberger R, Cremer C and Dithmar S (2010) Hochauflösende Fluoreszenzmikroskopie des retinalen Pigmentepithels mittels strukturierter Beleuchtung. Der Ophthalmol, 107:1037–1042 Link
Baddeley D, Chagin VO, Schermelleh L, Martin S, Pombo A, Carlton PM, Gahl A, Domaing P, Birk U, Leonhardt H, Cremer C and Cardoso MC (2010) Measurement of replication structures at the nanometer scale using super-resolution light microscopy. Nucleic Acids Res, 38:e8 Link
Baddeley D, Weiland Y, Batram C, Birk U and Cremer C (2010) Model based precision structural measurements on barely resolved objects. J Microsc, 237:70–78 Link
Bohn M, Diesinger P, Kaufmann R, Weiland Y, Müller P, Gunkel M, von Ketteler A, Lemmer P, Hausmann M, Heermann DW and Cremer C (2010) Localization microscopy reveals expression-dependent parameters of chromatin nanostructure. Biophys J, 99:1358–1367 Link
Cremer C (2010) Licht aus dem Dunkeln. Phys J, 9:18–19 Link
Cremer C, von Ketteler A, Lemmer P, Kaufmann R, Weiland Y, Müller P, Hausmann M, Gunkel M, Ruckelshausen T, Baddeley D and Amberger R (2010) Far-field fluorescence microscopy of cellular structures at molecular optical resolution. Pages 1–35 in: Nanoscopy and Multidimensional Optical Fluorescence Microscopy (ed. Diaspro A), CRC Press, Boca Raton Link
Gröner N, Capoulade J, Cremer C and Wachsmuth M (2010) Measuring and imaging diffusion with multiple scan speed image correlation spectroscopy. Opt Express, 18:21225–21237 Link
Grossmann C, Schwarz-Finsterle J, Schmitt E, Birk U, Hildenbrand G, Cremer C, Trakhtenbrot L and Hausmann M (2010) Variations of the spatial fluorescence distribution in ABL gene chromatin domains measured in blood cell nuclei by SMI microscopy after COMBO – FISH labelling. Pages 688–695 in: Microscopy: Science, technology, applications and education (eds. Mender-Vila A & Diaz J), Formatex, Badajoz Link
Heride C, Ricoul M, Kiêu K, von Hase J, Guillemot V, Cremer C, Dubrana K and Sabatier L (2010) Distance between homologous chromosomes results from chromosome positioning constraints. J Cell Sci, 123:4063–4075 Link
Lang M, Jegou T, Chung I, Richter K, Münch S, Udvarhelyi A, Cremer C, Hemmerich P, Engelhardt J, Hell SW and Rippe K (2010) Three-dimensional organization of promyelocytic leukemia nuclear bodies. J Cell Sci, 123:392–400 Link
Markaki Y, Gunkel M, Schermelleh L, Beichmanis S, Neumann J, Heidemann M, Leonhardt H, Eick D, Cremer C and Cremer T (2010) Functional nuclear organization of transcription and DNA replication: A topographical marriage between chromatin domains and the interchromatin compartment. Cold Spring Harb Symp Quant Biol, 75:475–492 Link
Müller P, Schmitt E, Jacob A, Hoheisel J, Kaufmann R, Cremer C and Hausmann M (2010) COMBO-FISH enables high precision localization microscopy as a prerequisite for nanostructure analysis of genome loci. Int J Mol Sci, 11:4094–4105 Link
Rouquette J, Cremer C, Cremer T and Fakan S (2010) Functional nuclear architecture studied by microscopy: Present and future.Int Rev Cell Mol Biol, 282:1–90 Link
Tykocinski L-O, Sinemus A, Rezavandy E, Weiland Y, Baddeley D, Cremer C, Sonntag S, Willecke K, Derbinski J and Kyewski B (2010) Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells. Proc Natl Acad Sci USA, 107:19426–19431 Link
2009
Baddeley D, Jayasinghe ID, Cremer C, Cannell MB and Soeller C (2009) Light-induced dark states of organic fluochromes enable 30 nm resolution imaging in standard media. Biophys J, 96:L22–L24 Link
Cremer C (2009) Lichtoptische Nanoskopie. Biospektrum, 27–30 Link
Gunkel M, Erdel F, Rippe K, Lemmer P, Kaufmann R, Hörmann C, Amberger R and Cremer C (2009) Dual color localization microscopy of cellular nanostructures. Biotechnol J, 4:927–938 Link
Lemmer P, Gunkel M, Weiland Y, Müller P, Baddeley D, Kaufmann R, Urich A, Eipel H, Amberger R, Hausmann M and Cremer C (2009) Using conventional fluorescent markers for far-field fluorescence localization nanoscopy allows resolution in the 10-nm range. J Microsc, 235:163–171 Link
2008
Batram C, Baddeley D, Kreth G and Cremer C (2008) High precision size measurement of centromere 8 and the 8q24/c-myc gene region in metaphase and interphase human fibroblasts indicate differential condensation. J Struct Biol, 164:293–303 Link
Birk UJ, Baddeley D and Cremer C (2008) Nanosizing by spatially modulated illumination (SMI) microscopy and applications to the nucleus. Pages 389–401 in: The Nucleus; Methods in Molecular Biology, vol. 2 (ed. Hancock R), Humana Press, New York ISBN 978-1-61737-898-0
Friedland W, Paretzke HG, Ballarini F, Ottolenghi A, Kreth G and Cremer C (2008) First steps towards systems radiation biology studies concerned with DNA and chromosome structure within living cells. Radiat Environ Biophys, 47:49–61 Link
Lemmer P, Gunkel M, Baddeley D, Kaufmann R, Urich A, Weiland Y, Reymann J, Müller P, Hausmann M and Cremer C (2008) SPDM: Light microscopy with single-molecule resolution at the nanoscale. Appl Phys B, 93:1–12 Link
Rauch J, Knoch TA, Solovei I, Teller K, Stein S, Buiting K, Horsthemke B, Langowski J, Cremer T, Hausmann M and Cremer C (2008) Light optical precision measurements of the active and inactive Prader–Willi syndrome imprinted regions in human cell nuclei. Differentiation, 76:66–82 Link
Reymann J, Baddeley D, Gunkel M, Lemmer P, Stadter W, Jegou T, Rippe K, Cremer C and Birk U (2008) High-precision structural analysis of subnuclear complexes in fixed and live cells via spatially modulated illumination (SMI) microscopy. Chromosom Res, 16:367–382 Link
Ronneberger O, Baddeley D, Scheipl F, Verveer PJ, Burkhardt H, Cremer C, Fahrmeir L, Cremer T and Joffe B (2008) Spatial quantitative analysis of fluorescently labeled nuclear structures: Problems, methods, pitfalls. Chromosom Res, 16:523–562 Link
2007
Baddeley D, Batram C, Weiland Y, Cremer C and Birk UJ (2007) Nanostructure analysis using spatially modulated illumination microscopy. Nat Protoc, 2:2640–2646 Link
Birk UJ, Upmann U, Wagner C and Cremer C (2007) Size estimation of protein clusters in the nanometer range by using spatially modulated illumination microscopy. Pages 272–279 in: Modern research and educational topics in microscopy, vol. 1 (eds. Méndez-Vilas A & Díaz J), Formatex, Badajoz ISBN-13: 978-84-611-9419-3
Brianna Caddle L, Grant JL, Szatkiewicz J, van Hase J, Shirley B-J, Bewersdorf J, Cremer C, Arneodo A, Khalil A and Mills KD (2007) Chromosome neighborhood composition determines translocation outcomes after exposure to high-dose radiation in primary cells. Chromosom Res, 15:1061–1073 Link
Kreth G and Cremer C (2007) Chromatin structure and the formation of chromosomal alterations. Pages 201–209 in: Chromosomal alterations: Methods, results and importance in human health (ed. Vijayalaxmi GO), Springer, Berlin & Heidelberg Link
Kreth G, Pazhanisamy SK, Hausmann M and Cremer C (2007) Cell type-specific quantitative predictions of radiation-induced chromosome aberrations: A computer model approach. Radiat Res, 167:515–525 Link
Mathée H, Baddeley D, Wotzlaw C, Cremer CG and Birk UJ (2007) Spatially modulated illumination microscopy using one objective lens. Opt Eng, 46:083603 Link
Schwarz-Finsterle J, Stein S, Groβmann C, Schmitt E, Trakhtenbrot L, Rechavi G, Amariglio N, Cremer C and Hausmann M (2007) Comparison of triple helical COMBO-FISH and standard FISH by means of quantitative microscopic image analysis of abl/bcr positions in cell nuclei. J Biochem Biophys Methods, 70:397–406 Link