Ageing, Developmental Biology & Disease at IMB
With advanced age, individuals become more prone to serious, long-term illnesses, such as cancer, cardiovascular disease and neurodegeneration.…
RNA Biology at IMB
RNA is responsible for carrying out a wide variety of essential tasks in the cell. Messenger RNAs encode information for producing proteins, while a host of non-coding RNAs (e.g.…
Proteostasis & Phase Separation at IMB
Proper cell function is dependent on the proteins and other molecules in the cell being correctly folded and organised. One way cells do this is by phase…
Regulation of heterochromatin in response to genotoxic stress
The epigenetic memory of a cell is shaped by pathways that establish, erase and maintain chromatin marks. Lysine 9 methylation on…
2022
Delaney CE, Methot SP, Kalck V, Seebacher J, Hess D, Gasser SM and Padeken J (2022) SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated…