Regulation of heterochromatin in response to genotoxic stress
The epigenetic memory of a cell is shaped by pathways that establish, erase and maintain chromatin marks. Lysine 9 methylation on…
2022
Delaney CE, Methot SP, Kalck V, Seebacher J, Hess D, Gasser SM and Padeken J (2022) SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated…
Jan Padeken
Positions held Since 2022: Group Leader, Institute of Molecular Biology (IMB), Mainz 2013 - 2022: Postdoctoral researcher, Friedrich Miescher Institute, BaselEducation 2013: …
Skin immunology & immunotherapy of skin tumours
Within my research group, we work to pursue several aspects of cutaneous and general immunology research. Most of our projects are located in the…
2022
Haist M, Stege H, Ebner R, Fleischer MI, Loquai C and Grabbe S (2022) The role of treatment sequencing with immune-checkpoint inhibitors and BRAF/MEK inhibitors for response and survival of…
Stephan Grabbe
Positions held Since 2022: Adjunct Clinician, Institute of Molecular Biology (IMB), Mainz Since 2007: Director (W3), Dept. of Dermatology, University Medical Center (UMC), Mainz…
Human microbiome ecology
The Vieira-Silva Lab explores the ecology of host-associated microbial communities, with a focus on the human gastrointestinal tract. Our research focuses on understanding…