2019

Bender K, Vydzhak O, Klermund J, Busch A, Grimm S and Luke B (2019) Checkpoint adaptation in repair-deficient cells drives aneuploidy and resistance to genotoxic agents. BioRxiv doi: 10.1101/464685 Link

Jolivet P, Serhal K, Graf M, Eberhard S, Xu Z, Luke B and Teixeira MT (2019) A subtelomeric region affects telomerase-negative replicative senescence in Saccharomyces cerevisiae. Sci Rep, 9:1845 Link

Lockhart A, Pires VB, Bento F, Kellner V, Luke-Glaser S, Yakoub G, Ulrich HD and Luke B (2019) RNase H1 and H2 Are Differentially Regulated to Process RNA-DNA Hybrids. Cell Rep, 29:2890–2900.e5 Link

Schmidt TT, Sharma S, Reyes GX, Kolodziejczak A, Wagner T, Luke B, Hofer A, Chabes A and Hombauer H (2019) Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio. Nucleic Acids Res, doi: 10.1093/nar/gkz1006 Link

2018

Luke B (2018) Telomere regulation. Differentiation, 102:27–29 (guest editor of the issue) Link

Michelini F, Jalihal AP, Francia S, Meers C, Neeb ZT, Rossiello F, Gioia U, Aguado J, Jones-Weinert C, Luke B, Biamonti G, Nowacki M, Storici F, Carninci P, Walter NG and d’Adda di Fagagna F (2018) From “cellular” RNA to “smart” RNA: Multiple roles of RNA in genome stability and beyond. Chem Rev, 118:4365–4403 Link

Misino S, Bonetti D, Luke-Glaser S and Luke B (2018) Increased TERRA levels and RNase H sensitivity are conserved hallmarks of post-senescent survivors in budding yeast. Differentiation, 100:37–45 Link

2017

Graf M*, Bonetti D*, Lockhart A*, Serhal K, Kellner V, Maicher A, Jolivet P, Teixeira MT and Luke B (2017) Telomere length determines TERRA and R-loop regulation through the cell cycle. Cell, 170:72–85 (*indicates joint contribution) Link

Lafuente-Barquero J, Luke-Glaser S, Graf M, Silva S, Gómez-González B, Lockhart A, Lisby M, Aguilera A and Luke B (2017) The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage. PLOS Genet, 13:e1007136 Link

2016

Buser R*, Kellner V*, Melnik A, Wilson-Zbinden C, Schellhaas R, Kastner L, Piwko W, Dees M, Picotti P, Maric M, Labib K, Luke B# and Peter M# (2016) The replisome-coupled E3 ubiquitin ligase Rtt101Mms22 counteracts Mrc1 function to tolerate genotoxic stress. PLOS Genet, 12:e1005843 (*indicates joint authorship, #indicates joint correspondence) Link

Dieckmann AK, Babin V, Harari Y, Eils R, König R, Luke B# and Kupiec M# (2016) Role of the ESCRT complexes in telomere biology. MBio, 7:e01793-16 (#indicates joint correspondence) Link

Poos AM, Maicher A, Dieckmann AK, Oswald M, Eils R, Kupiec M, Luke B and König R (2016) Mixed integer linear programming based machine learning approach identifies regulators of telomerase in yeast. Nucleic Acids Res, 44:e93 Link

Silva S, Altmannova V, Luke-Glaser S, Henriksen P, Gallina I, Yang X, Choudhary C, Luke B, Krejci L and Lisby M (2016) Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance. Genes Dev, 30:700–717 Link

Styles EB, Founk KJ, Zamparo LA, Sing TL, Altintas D, Ribeyre C, Ribaud V, Rougemont J, Mayhew D, Costanzo M, Usaj M, Verster AJ, Koch EN, Novarina D, Graf M, Luke B, Muzi-Falconi M, Myers CL, Mitra RD, Shore D, Brown GW, Zhang Z, Boone C and Andrews BJ (2016) Exploring quantitative yeast phenomics with single-cell analysis of DNA damage foci. Cell Syst, 3:264–277.e10 Link

2015

Feuerhahn S, Chen L, Luke B# and Porro A# (2015) No DDRama at chromosome ends: TRF2 takes centre stage. Trends Biochem Sci, 40:275–285 (#indicates joint correspondence) Link

Rippe K# and Luke B# (2015) TERRA and the state of the telomere. Nat Struct Mol Biol, 22:853–858 (#indicates joint correspondence) Link

Stockklausner C*, Raffel S*, Klermund J, Bandapalli OR, Beier F, Brümmendorf TH, Bürger F, Sauer SW, Hoffmann GF, Lorenz H, Tagliaferri L, Nowak D, Hofmann WK, Buergermeister R, Kerber C, Rausch T, Korbel JO, Luke B#, Trumpp A# and Kulozik AE# (2015) A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition. Aging, 7:911–927 (*indicates joint contribution, #indicates joint correspondence) Link

2014

Balk B, Dees M, Bender K and Luke B (2014) The differential processing of telomeres in response to increased telomeric transcription and RNA-DNA hybrid accumulation. RNA Biol, 11:95–100 Link

Klermund J, Bender K and Luke B (2014) High nutrient levels and TORC1 activity reduce cell viability following prolonged telomere dysfunction and cell cycle arrest. Cell Rep, 9:324–335 Link

Maicher A, Lockhart A and Luke B (2014) Breaking new ground: Digging into TERRA function. Biochim Biophys Acta - Gene Regul Mech, 1839:387–394 Link

2013

Balk B*, Maicher A*, Dees M, Klermund J, Luke-Glaser S, Bender K and Luke B (2013) Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence. Nat Struct Mol Biol, 20:1199–1205 (*indicates joint contribution) Link

2012

Luke-Glaser S and Luke B (2012) The Mph1 helicase can promote telomere uncapping and premature senescence in budding yeast. PLOS One, doi: 10.1371/journal.pone.0042028 Link

Luke-Glaser S, Poschke H and Luke B (2012) Getting in (and out of) the loop: Regulating higher order telomere structures. Front Oncol, 2:180 Link

Maicher A, Kastner L, Dees M and Luke B (2012) Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence. Nucleic Acids Res, 40:6649–6659 Link

Maicher A*, Kastner L* and Luke B (2012) Telomeres and disease: Enter TERRA. RNA Biol, 9:843–849 (*indicates joint contribution) Link

Poschke H*, Dees M*, Chang M, Amberkar S, Kaderali L, Rothstein R and Luke B (2012) Rif2 promotes a telomere fold-back structure through Rpd3L recruitment in budding yeast. PLOS Genet, 8:e1002960 (*indicates joint contribution) Link

2011

Ferreira HC, Luke B, Schober H, Kalck V, Lingner J and Gasser SM (2011) The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast. Nat Cell Biol, 13:867–874 Link

Iglesias N, Redon S, Pfeiffer V, Dees M, Lingner J# and Luke B# (2011) Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast. EMBO Rep, 12:587–593 (#indicates joint correspondence) Link

2010

Luke-Glaser S, Luke B, Grossi S and Constantinou A (2010) FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling. EMBO J, 29:795–805 Link

2009

Chang M, Luke B, Kraft C, Li Z, Peter M, Lingner J and Rothstein R (2009) Telomerase is essential to alleviate Pif1-induced replication stress at telomeres. Genetics, 183:779–791 Link

Deplazes A, Möckli N, Luke B, Auerbach D and Peter M (2009) Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control. EMBO J, 28:1429–1441 Link

Luke B and Lingner J (2009) TERRA: Telomeric repeat-containing RNA. EMBO J, 28:2503–2510 Link