Publications co-authored by the Microscopy Core Facility


Bluhm A, Viceconte N, Li F, Rane G, Ritz S, Wang S, Levin M, Shi Y, Kappei D and Butter F (2019) ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2. Nucleic Acids Res, 47:1896–1907 Link

Liskayová G, Hubčík L, Búcsi A, Fazekaš T, Martínez JC, Devínsky F, Pisárčik M, Hanulová M, Ritz S and Uhríková D (2019) pH-Sensitive N,N-Dimethylalkane-1-amine N-Oxides in DNA delivery: From structure to transfection efficiency. Langmuir, 35:13382–13395 Link

Liu X, Chen S-Y, Chen Q, Yao X, Gelléri M, Ritz S, Kumar S, Cremer C, Landfester K, Müllen K, Parekh S, Narita A and Bonn M (2019) Nanographenes: Ultrastable, switchable, and bright probes for super-resolution microscopy. Angew Chemie Int Ed, doi:10.1002/anie.201909220 Link

Schultheis D, Schwirz J and Frasch M (2019) RNAi screen in Tribolium reveals involvement of F-BAR proteins in myoblast fusion and visceral muscle morphogenesis in insects. G3-Genes Genomes Genet, 9:1141–1151 Link

Schultheis D, Weißkopf M, Schaub C, Ansari S, Dao VA, Grossmann D, Majumdar U, Hakeemi MS, Troelenberg N, Richter T, Schmitt-Engel C, Schwirz J, Ströhlein N, Teuscher M, Bucher G and Frasch M (2019) A large scale systemic RNAi screen in the red flour beetle Tribolium castaneum identifies novel genes involved in insect muscle development. G3-Genes Genomes Genet, 9:1009–1026 Link

Wong RP, García-Rodríguez N, Zilio N, Hanulová M and Ulrich HD (2019) Processing of DNA Polymerase-Blocking Lesions during Genome Replication Is Spatially and Temporally Segregated from Replication Forks. Mol Cell, doi: 10.1016/j.molcel.2019.09.015 Link


Hubčík L, Galliková D, Pullmannová P, Lacinová Ľ, Sulová Z, Hanulová M, Funari SS, Devínsky F and Uhríková D (2018) DNA-DOPE-gemini surfactants complexes at low surface charge density: From structure to transfection efficiency. Gen Physiol Biophys, 37:57–69 Link

Momper R, Steinbrecher J, Dorn M, Rörich I, Bretschneider S, Tonigold M, Ramanan C, Ritz S, Mailänder V, Landfester K and Bannwarth MB (2018) Enhanced photoluminescence properties of a carbon dot system through surface interaction with polymeric nanoparticles. J Colloid Interface Sci, 518:11–20 Link

Reinholz J, Diesler C, Schöttler S, Kokkinopoulou M, Ritz S, Landfester K and Mailänder V (2018) Protein machineries defining pathways of nanocarrier exocytosis and transcytosis. Acta Biomater, 71:432–443 Link

Seiwert D, Witt H, Ritz S, Janshoff A and Paulsen H (2018) The nonbilayer lipid MGDG and the major light-harvesting complex (LHCII) promote membrane stacking in supported lipid bilayers. Biochemistry, 57:2278–2288 Link


Landgraf L, Nordmeyer D, Schmiel P, Gao Q, Ritz S, Gebauer JS, Graß S, Diabaté S, Treuel L, Graf C, Rühl E, Landfester K, Mailänder V, Weiss C, Zellner R and Hilger I (2017) Validation of weak biological effects by round robin experiments: Cytotoxicity/biocompatibility of SiO2 and polymer nanoparticles in HepG2 cells. Sci Rep, 7:4341 Link

Ng DYW, Vill R, Wu Y, Koynov K, Tokura Y, Liu W, Sihler S, Kreyes A, Ritz S, Barth H, Ziener U and Weil T (2017) Directing intracellular supramolecular assembly with N-heteroaromatic quaterthiophene analogues. Nat Commun, 8:1850 Link


Kaloyanova S, Zagranyarski Y, Ritz S, Hanulová M, Koynov K, Vonderheit A, Müllen K and Peneva K (2016) Water-soluble NIR-absorbing rylene chromophores for selective staining of cellular prganelles. J Am Chem Soc, 138:2881–2884 Link

Liu W, Naydenov B, Chakrabortty S, Wuensch B, Hübner K, Ritz S, Cölfen H, Barth H, Koynov K, Qi H, Leiter R, Reuter R, Wrachtrup J, Boldt F, Scheuer J, Kaiser U, Sison M, Lasser T, Tinnefeld P, Jelezko F, Walther P, Wu Y and Weil T (2016) Fluorescent nanodiamond-gold hybrid particles for multimodal optical and electron microscopy cellular imaging. Nano Lett, 16:6236–6244 Link


Lerch S*, Ritz S*, Bley K, Messerschmidt C, Weiss CK, Musyanovych A, Landfester K and Mailänder V (2015) Nanoprobing the acidification process during intracellular uptake and trafficking. Nanomedicine, 11:1585–1596 (*indicates equal contribution) Link

Zaba C, Ritz S, Tan C-WD, Zayni S, Müller M, Reuning U and Sinner E-K (2015) Functional cell adhesion receptors (integrins) in polymeric architectures. ChemBioChem, 16:1740–1743 Link


Boutter J, Huang Y, Marovca B, Vonderheit A, Grotzer MA, Eckert C, Cario G, Wollscheid B, Horvath P, Bornhauser BC and Bourquin J-P (2014) Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support. Oncotarget, 5:11501–11512 Link

Holloschi A, Ritz S, Schäfer I and Kioschis P (2014) Analysis of huntingtin aggregation by fluorescence and FRET microscopy. Pages 217–215 in: Microscopy: Advances in scientific research and education, vol. 1 (ed. Méndez-Vilas A), Formatex, Badajoz  Link

Rämö P, Drewek A, Arrieumerlou C, Beerenwinkel N, Ben-Tekaya H, Cardel B, Casanova A, Conde-Alvarez R, Cossart P, Csúcs G, Eicher S, Emmenlauer M, Greber U, Hardt W-D, Helenius A, Kasper C, Kaufmann A, Kreibich S, Kühbacher A, Kunszt P, Low SH, Mercer J, Mudrak D, Muntwiler S, Pelkmans L, Pizarro-Cerdá J, Podvinec M, Pujadas E, Rinn B, Rouilly V, Schmich F, Siebourg-Polster J, Snijder B, Stebler M, Studer G, Szczurek E, Truttmann M, von Mering C, Vonderheit A, Yakimovich A, Bühlmann P and Dehio C (2014) Simultaneous analysis of large-scale RNAi screens for pathogen entry. BMC Genomics, 15:1162 Link


Persch N, Elhayek A, Welk M, Bruhn A, Grewenig S, Böse K, Kraegeloh A and Weickert J (2013) Enhancing 3-D cell structures in confocal and STED microscopy: A joint model for interpolation, deblurring and anisotropic smoothing. Meas Sci Technol, 24:125703 Link

Publications acknowledging the Microscopy Core Facility



Zimmermann T, Maroso M, Beer A, Baddenhausen S, Ludewig S, Fan W, Vennin C, Loch S, Berninger B, Hofmann C, Korte M, Soltesz I, Lutz B and Leschik J. (2018). Neural stem cell lineage-specific cannabinoid type-1 receptor regulates neurogenesis and plasticity in the adult mouse hippocampusCerebral Cortex, 28, 4458–4471.

Schink A, Neumann J, Leifke AL, Ziegler K, Fröhlich-Nowoisky J, Cremer C, Thines E, Weber B, Pöschl U, Schuppan D and Lucas K. (2018). Screening of herbal extracts for TLR2- and TLR4-dependent anti-inflammatory effectsPLoS ONE, 13: e0203907.  

Almeida MV, Dietz S, Redl S, Karaulanov E, Hildebrandt A, Renz C, Ulrich HD, König J, Butter F and Ketting RF. (2018). GTSF‐1 is required for formation of a functional RNA‐dependent RNA polymerase complex in Caenorhabditis elegansEMBO J, 37: e99325.

García‐Rodríguez N, Morawska M, Wong RP, Daigaku Y and Ulrich HD. (2018). Spatial separation between replisome‐ and template‐induced replication stress signalingEMBO J, 37: e98369.

Moscariello P, Ng DYW, Jansen M, Weil T, Luhmann HJ and Hedrich J. (2018). Brain delivery of multifunctional dendrimer protein bioconjugates. Adv. Sci, 5: 1700897.

Fritzsch C, Baumgärtner S, Kuban M, Steinshorn D, Reid G and Legewie S. (2018). Estrogen‐dependent control and cell‐to‐cell variability of transcriptional burstingMol Syst Biol, 14: e7678.


Blanquie O, Yang J-W, Kilb W, Sharopov S, Sinning A and Luhmann HJ. (2017). Electrical activity controls area-specific expression of neuronal apoptosis in the developing mouse cerebral cortexeLife, 6: 1-21.

Chitale S and Richly H. (2017). Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylationOncotarget, 8: 30870-30887.

Dzama MM, Nigmatullina L, Sayols S, Kreim N and Soshnikova N. (2017). Distinct populations of embryonic epithelial progenitors generate Lgr5+ intestinal stem cellsDev Biol, 432: 258-264.

Graf M, Bonetti D, Lockhart A, Serhal K, Kellner V, Maicher A, Jolivet P, Teixeira MT and Luke B. (2017). Telomere length determines TERRA and R-Loop regulation through the cell cycleCell, 170: 72-85.

Kazakevych J, Sayols S, Messner B, Krienke C and Soshnikova N. (2017). Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cellsNucleic Acids Res, 45: 5770-5784.

Lebedeva S, de Jesus Domingues AM, Butter F and Ketting RF. (2017). Characterization of genetic loss-of-function of Fus in zebrafishRNA Biol, 14: 29-35.

Navandar M, Garding A, Kumar Sahu S, Pataskar A, Schick S and Tiwari VK. (2017). ERK signalling modulates epigenome to drive epithelial to mesenchymal transitionOncotarget, 8: 29269-29281.

Nigmatullina L, Norkin M, Dzama MM, Messner B, Sayols S and Soshnikova N. (2017). Id2 controls specification of Lgr5(+) intestinal stem cell progenitors during gut developmentEMBO J, 36: 869-885.

Szczurek A, Klewes L, Xing J, Gourram A, Birk U, Knecht H, Dobrucki JW, Mai S and Cremer C. (2017). Imaging chromatin nanostructure with binding-activated localization microscopy based on DNA structure fluctuationsNucleic Acids Res, 45: e56.

Wilhelm T, Byrne J, Medina R, Kolundžić E, Geisinger J, Hajduskova M, Tursun B and Richly H. (2017). Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. ElegansGenes Dev, 31: 1561-1572.


Blanquie O, Liebmann L, Hübner CA, Luhmann HJ and Sinning A. (2016). NKCC1-mediated GABAergic signaling promotes postnatal Cell death in neocortical Cajal-Retzius cellsCereb Cortex, 27: 1644-1659.

Kaymak A and Richly H. (2016). Zrf1 controls mesoderm lineage genes and cardiomyocyte differentiationCell Cycle, 15: 3306-3317.


Hirsch M and Helm M. (2015). Live cell imaging of duplex siRNA intracellular traffickingNucleic Acids Res, 43: 4650-60.

Roovers EF, Rosenkranz D, Mahdipour M, Han CT, He N, de Sousa Lopes SMC, van der Westerlaken LA, Zischler H, Butter F, Roelen BA and Ketting RF. (2015). Piwi proteins and piRNAs in mammalian oocytes and early embryosCell Reports, 10: 2069-2082.

Sakry D, Yigit H, Dimou L and Trotter J. (2015). Oligodendrocyte precursor cells synthesize neuromodulatory factorsPLoS One, 10: e0127222.

Stangenberg R, Wu Y, Hedrich J, Kurzbach D, Wehner D, Weidinger G, Kuan SL, Jansen MI, Jelezko F, Luhmann HJ, Hinderberger D, Weil T and Müllen K. (2015). A polyphenylene dendrimer drug transporter with precisely positioned amphiphilic surface patches. Adv Healthc Mater, 4: 377-384.


Bühler J, Gietzen S, Reuter A, Kappel C, Fischer K, Decker S, Schäffel D, Koynov K, Bros M, Tubbe I, Grabbe S and Schmidt M. (2014). Selective uptake of cylindrical poly(2-oxazoline) brush-antidec205 antibody-ova antigen conjugates into dec-positive dendritic cells and subsequent t-cell activationChemistry, 20: 12405-12410.

Fritz T, Hirsch M, Richter FC, Müller SS, Hofmann AM, Rusitzka KAK, Markl J, Massing U, Frey H and Helm M. (2014). Click modification of multifunctional liposomes bearing hyperbranched polyether chainsBiomacromolecules, 15: 2440-2448.

Hamm R, Chen YR, Seo EJ, Zeino M, Wu CF, Müller R, and Yang NS and Efferth T. (2014). Induction of cholesterol biosynthesis by archazolid B in {T24} bladder cancer cellsBiochem Pharmacol, 91: 18-30.

Hamm R, Zeino M, Frewert S and Efferth T. (2014). Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid BToxicol Appl Pharmacol, 281: 78-86.

Malone CD, Mestdagh C, Akhtar J, Kreim N, Deinhard P, Sachidanandam R, Treisman J and Roignant JY. (2014). The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcriptGenes Dev, 28: 1786-1799.


Thakurela S, Garding A, Jung J, Schübeler D, Burger L and Tiwari VK. (2013). Gene regulation and priming by topoisomerase IIα in embryonic stem cellsNat Commun, 4: 2478.

Tiwari N, Tiwari V, Waldmeier L, Balwierz P, Arnold P, Pachkov M, Meyer-Schaller N, Schübeler D, van Nimwegen E and Christofori G. (2013). Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogrammingCancer Cell, 23: 768-783.

Zehender CM, Librizzi L, Hedrich J, Bauer NM, Angamo EA, De Curtis M and Luhmann HJ. (2013). Moderate hypoxia followed by reoxygenation results in blood-brain barrier breakdown via oxidative stress-dependent tight-junction protein disruptionPLoS One, 8: e82823.

Zehender CM, Tsohataridis S, Luhmann HJ and Yang JW. (2013). Developmental switch inneurovascular coupling in the immature rodent barrel cortexPLoS One, 8: e80749.

Zehender CM, Wedler HE and Luhmann HJ. (2013). A novel in vitro model to study pericytes in the neurovascular unit of the developing cortexPLoS One, 8: e81637.


Gierl MS, Gruhn H, von Seggern A, Maltry N and Niehrs C. (2012). GADD45G functions in male sex deter-mination by promoting p38 signaling and sry expressionDev Cell, 23: 1032-1042.