The epitranscriptome in regulation of neuronal development

Jean-Yves Roignant

Positions held

  • Since 2012: Group Leader, Institute of Molecular Biology (IMB), Mainz
  • 2008-2011: Research Associate, Skirball Institute of Biomolecular Medicine, New York University
  • 2003-2008: Postdoctoral Fellow, Skirball Institute of Biomolecular Medicine, New York University


  • 2003: PhD in Developmental Biology, Jacques Monod Institute, Paris
  • 1997: BSc in Molecular and Cellular Biology, Rennes

Most relevant publications by Jean-Yves Roignant

Lence T, Akhtar J, Bayer M, Schmid K, Spindler L, Ho CH, Kreim N, Andrade- Navarro MA, Poeck B, Helm M, Roignant JY (2016). m6A controls neurogenesis and sex determination in Drosophila via its nuclear reader protein YT521-B. Nature, 540, 242-247

Malone CD, Mestdagh C, Akhtar J, Kreim N, Deinhard P, Sachidanandam R, Treisman J and Roignant JY (2014). The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript. Genes Dev, 28, 1786-1799

Roignant JY and Treisman JE (2010). Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene. Cell, 143, 238-250

Roignant JY, Legent K, Janody F and Treisman JE (2010). The transcriptional cofactor Chip acts with LIM-homeodomain proteins to set the boundary of the eye field in Drosophila. Dev, 137, 273-281

Roignant JY and Treisman JE (2009). Pattern Formation of the Drosophila Eye Disc. Int J Dev Biol, 53, 795-804

Miura GI, Roignant JY, Wassef M and Treisman JE (2008). Myopic acts in the endocytic pathway to enhance signaling by the Drosophila EGF receptor. Dev, 135, 1913-1922

Roignant JY, Hamel S, Janody F and Treisman JE (2006). The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathway. Genes Dev, 20, 795-806


  Research website