Lineage reprogramming glia into neurons

Benedikt Berninger

Positions held

  • Since 2018: Professor, Institute of Psychiatry, Psychology & Neuroscience, Centre of Developmental Neurobiology, King's College London, UK
  • Since 2012: Professor, University Medical Center of the Johannes Gutenberg University Mainz
  • 2011-2012: Senior Lecturer in Physiology, Department of Physiological Genomics, Ludwig-Maximilians University Munich
  • 2005: Lecturer in Physiology, Department of Physiological Genomics, Ludwig-Maximilians University Munich
  • 2003-2005: Senior Research Associate at the Institute of Stem Cell Research, Helmholtz Zentrum Munich
  • 2000-2003: Group leader at the Department of Neuroimmunology, Max Planck Institute of Neurobiology

Education

  • 2011: Habilitation and venia legendi, Faculty of Medicine (Physiology), Ludwig-Maximilians University Munich
  • 1993-1996: PhD with Dr. H. Thoenen, Max-Planck Institute of Psychiatry (now Neurobiology), Martinsried/Munich
  • 1992: Diploma in Biology, Ludwig-Maximilians University Munich

Recent publications by Benedikt Berninger

Karow M, Camp JG, Falk S, Gerber T, Pataskar A, Gac-Santel M, Kageyama J, Brazovskaja A, Garding A, Fan W, Riedemann T, Casamassa A, Smiyakin A, Schichor C, Götz M, Tiwari VK, Treutlein B, Berninger B (2018). Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program. Nat Neurosci, doi: 10.1038/s41593-018-0168-3

Zhao S, Fan W, Guo X, Xue L, Berninger B, Salierno MJ, Del Campo A (2018). Microenvironments to study migration and somal translocation in cortical neurons. Biomaterials, 156:238-247

Bicker F, Vasic V, Horta G, Ortega F, Nolte H, Kavyanifar A, Keller S, Stankovic ND, Harter PN, Benedito R, Lutz B, Bäuerle T, Hartwig J, Baumgart J, Krüger M, Radyushkin K, Alberi L, Berninger B, Schmidt MHH (2017). Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception. Nat Commun. 8, 15922.

Dehorter N, Marichal N, Marín O, Berninger B (2017). Tuning neural circuits by turning the interneuron knob. Curr Opin Neurobiol. 42, 144-151

Kleiderman S, Gutbier S, Ugur Tufekci K, Ortega F, Sá JV, Teixeira AP, Brito C, Glaab E, Berninger B, Alves PM, Leist M (2017). Conversion of Nonproliferating Astrocytes into Neurogenic Neural Stem Cells: Control by FGF2 and Interferon-γ. Stem Cells. 34, 2861-2874

Gascón S, Mureno E, Masserdotti G, Ortega F, Russo GL, Petrik D, Deshpande A, Heinrich C, Karow M, Roberston SP, Schroeder T, Beckers J, Irmler M, Berndt C, Friedmann Angeli JP, Conrad M, Berninger B and Götz M (2016). Identification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming. Cell Stem Cell, 18, 396-409

Research website