Epigenetic Regulation of Development and Disease

Vijay Tiwari

Positions held

  • Since 2012: Group Leader, Institute of Molecular Biology (IMB), Mainz
  • 2008-2011: Postdoc, Friedrich Miescher Institute for Biomedical Research, Basel
  • 2006-2008: Postdoc, Johns Hopkins University School of Medicine, Baltimore

Education

  • 2006: PhD in Developmental Biology, Uppsala University
  • 2002: MSc in Molecular and Human Genetics, Banaras University, Varanasi

Most relevant publications by Vijay Tiwari

Pataskar A*, Jung J*, Smialowski P, Noack F, Calegari F, Straub T and Tiwari VK (2016). NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program. EMBO J, 35, 24-45. 

Thakurela S*, Sahu SK*, Garding A and Tiwari VK (2015). Dynamics and function of distal regulatory elements during neurogenesis and neuroplasticity. Genome Res, 25, 1309-24.

Sahu SK, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, Ortega F, Schmarowski N, Berninger B, Nitsch R, Schmidt M and Tiwari VK (2015). JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J, 34, 2162-2181.

Thakurela S*, Garding A*, Jung J, Schübeler D, Burger L, Tiwari VK (2013). Gene regulation and priming by topoisomerase IIα in embryonic stem cells. Nat Commun, 4, 2478.

Tiwari VK*, Burger L, Nikoletopoulou V, Deogracias R, Thakurela S, Wirbelauer C, Kaut J, Terranova R, Hoerner L, Mielke C, Boege F, Murr R, Peters AH, Barde YA and Schübeler D* (2012). Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state. Proc Nat Acad Sci U S A, 190, E934-E943.

Tiwari VK, Stadler M, Wirbelauer C, Paro R, Beisel C and Schübeler D (2011). A Chromatin-modifying Function of JNK during Stem Cell Differentiation. Nat Genet, 44, 94-100.

Stadler MB, Murr R, Burger L, Ivanek R, Lienert F, Schöler A, Wirbelauer C, Oakeley EJ, Gaidatzis D, Tiwari VK and Schübeler D (2011). Transcription factor binding dynamically shapes the mouse methylome at distal regulatory regions. Nature, 480, 490-495.

Bell O, Tiwari VK, Thomä NH and Schübeler D (2011). Dynamics and determinants of DNA accessibility. Nat Rev Genet, 12, 554-564.

(* indicates joint contribution; #indicates joint correspondence)

  Research website