Modelling of Biological Networks

Stefan Legewie

Positions held

  • Since 2010: Group Leader, Institute of Molecular Biology (IMB), Mainz
  • 2009-2010: Group Leader ‘Theoretical Systems Biology’, Department of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg
  • 2008-2009: Postdoctoral Researcher, Institute for Theoretical Biology, Humboldt University Berlin


  • 2008: PhD in Biophysics, Humboldt University, Berlin
  • 2004: Diploma in Biochemistry, University of Witten/Herdecke

Most cited publications by Stefan Legewie

Kamenz J, Mihaljev T, Kubis A, Legewie S* and Hauf S* (2015). Robust ordering of anaphase events by adaptive thresholds and competing degradation pathways. Molecular Cell, 60, 446-459 

Kallenberger S, Beaudouin J, Claus J, Fischer C, Sorger PK, Legewie S* and Eils R* (2014). Intra- and Interdimeric Caspase-8 Self-Cleavage Controls Strength and Timing of CD95-Induced Apoptosis. Science Signaling, 7, ra23 (* joint senior authors) (Editors’ Choice in Science 343: 1178)

Paulsen M*, Legewie S*, Eils R, Karaulanov E and Niehrs C (2011). Negative feedback in the bone morphogenetic Protein (BMP4) synexpression group governs its dynamic signaling range and canalizes development. Proc Natl Acad Sci U S A,  108, 10202-10207 (* joint first authors) (Editors’Choice in Science 333: 138, Rated Exceptional by F1000)


  Research website