Epigenetics of drug disposition and response

Leszek Wojnowski

Positions held

  • Since 2003: Professor of Pharmacology (C3), Department of Pharmacology, Mainz
  • 2001-2003: Group Leader, Department of Clinical Pharmacology, Göttingen
  • 1998-2001: Vice-President of Epidauros AG in Bernried
  • 1993-1998: Postdoc, NIH Bethesda
  • 1991-1993: Postdoc, Institute of Physiology, Würzburg

Education

  • 1991: German Medical Licence (Approbation)
  • 1991: Doctoral degree (summa cum laude), Institute of Physiology, Würzburg
  • 1982-1988: Study of Medicine, Medical Academy in Gdansk, Poland

Most cited publications by Leszek Wojnowski

Hustert E, Haberl M, Burk O, Wolbold R, He YQ, Klein K, Nuessler AC, Neuhaus P, Klattig J, Eiselt R, Koch I, Zibat A, Brockmoller J, Halpert JR, Zanger UM and Wojnowski L (2001). The genetic determinants of the CYP3A5 polymorphism. Pharmacogenetics, 11, 773-779

Wojnowski L, Zimmer AM, Beck TW, Hahn H, Bernal R, Rapp UR and Zimmer A (1997). Endothelial apoptosis in Braf-deficient mice. Nat Genet, 16, 293-297

Eiselt R, Domanski TL, Zibat A, Mueller R, Presecan-Siedel E, Hustert E, Zanger UM, Brockmoller J, Klenk HP, Meyer UA, Khan KK, He YA, Halpert JR and Wojnowski L (2001). Identification and functional characterization of eight CYP3A4 protein variants. Pharmacogenetics, 11, 447-458

Hustert E, Zibat A, Presecan-Siedel E, Eiselt R, Mueller R, Fuss C, Brehm I, Brinkmann U, Eichelbaum M, Wojnowski L and Burk O (2001). Natural protein variants of pregnane x receptor with altered transactivation activity toward cyp3a4. Drug Metab Dispos, 29, 1454-1459

Gellner K, Eiselt R, Hustert E, Arnold H, Koch I, Haberl M, Deglmann CJ, Burk O, Buntefuss D, Escher S, Bishop C, Koebe HG, Brinkmann U, Klenk HP, Kleine K, Meyer UA and Wojnowski L (2001). Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene. Pharmacogenetics, 11, 111-121

 

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