Epigenetics of drug disposition and response

Research website

Positions held

  • Since 2003: Professor of Pharmacology (C3), Department of Pharmacology, Johannes Gutenberg University (JGU), Mainz
  • 2001 - 2003: Group Leader, Department of Clinical Pharmacology, Göttingen
  • 1998 - 2001: Vice-President of Epidauros AG in Bernried
  • 1993 - 1998: Postdoc, NIH Bethesda
  • 1991 - 1993: Postdoc, Institute of Physiology, Würzburg

Education

  • 1991: German Medical Licence (Approbation)
  • 1991: Doctoral degree (summa cum laude), Institute of Physiology, Würzburg
  • 1982 - 1988: Study of Medicine, Medical Academy in Gdansk

Selected publications by Leszek Wojnowski

More P, Goedtel-Armbrust U, Shah V, Mathaes M, Kindler T, Andrade-Navarro MA, Wojnowski L (2019) Drivers of topoisomerase II poisoning mimic and complement cytotoxicity in AML cells. Oncotarget, 10(51):5298-5312 Link

Deng S, Yan T, Nikolova T, Fuhrmann D, Nemecek A, Gödtel-Armbrust U, Kaina B, Wojnowski L (2015) The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cells. Br J Pharmacol, 172(9):2246-57 Link

Mathäs M, Burk O, Qiu H, Nusshag C, Gödtel-Armbrust U, Baranyai D, Deng S, Römer K, Nem D, Windshügel B, Wojnowski L (2012) Evolutionary history and functional characterization of the amphibian xenosensor CAR.Mol Endocrinol, 26(1):14-26 Link

Qiu H, Mathäs M, Nestler S, Bengel C, Nem D, Gödtel-Armbrust U, Lang T, Taudien S, Burk O, Wojnowski L (2010) The unique complexity of the CYP3A4 upstream region suggests a nongenetic explanation of its expression variability. Pharmacogenet Genomics, 20(3):167-78 Link