Drosophila Development and RNA Processing

Jean-Yves Roignant

Positions held

  • Since 2012: Group Leader, Institute of Molecular Biology (IMB), Mainz
  • 2008-2011: Research Associate, Skirball Institute of Biomolecular Medicine, New York University
  • 2003-2008: Postdoctoral Fellow, Skirball Institute of Biomolecular Medicine, New York University


  • 2003: PhD in Developmental Biology, Jacques Monod Institute, Paris
  • 1997: BSc in Molecular and Cellular Biology, Rennes

Recent publications by Jean-Yves Roignant

Angelova M, Dinges N, Dimitrova D, Lence T, Worpenberg L, Carre C# and Roignant JY#. The emerging field of epitranscriptomics in neurodevelopmental and neuronal disorders. Front Bioeng Biotechnol, 6:46, doi: 10.3389/fbioe

Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, Biggiogera M, Helm M, Soller M, Bühler M and Roignant JY. (2018). Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m 6 A machinery component Wtap/Fl(2)d. Genes Dev, 32: 415–429.

Casas-Vila N, Bluhm A, Sayols S, Dinges N, Dejung M, Altenhein T, Kappei D, Altenhein B, Roignant JY and Butter F. (2017). The developmental proteome of Drosophila melanogaster. Genome Res, 27: 1273–1285.

Dinges N, Morin V, Kreim N, Southall TD and Roignant JY. (2017). Comprehensive Characterization of the Complex lola Locus Reveals a Novel Role in the Octopaminergic Pathway via Tyramine Beta-Hydroxylase Regulation. Cell Rep, 21: 2911–2925.

Lence T, Soller M and Roignant JY. (2017). A fly view on the roles and mechanisms of the m(6)A mRNA modification and its players. RNA Biol,  1–9.

Lence T, Akhtar J, Bayer M, Schmid K, Spindler L, Ho CH, Kreim N, Andrade- Navarro MA, Poeck B, Helm M, Roignant JY (2016). m6A controls neurogenesis and sex determination in Drosophila via its nuclear reader protein YT521-B. Nature, 540, 242-247

Research website