Targets of the NG2 intracellular domain in gene regulation in glial precursor cells

Jacqueline Trotter

Positions held

  • Since 2000: Professor of Cell Biology (C3), Dept. of Biology, JGU Mainz
  • 1999-2000: Hermann und Lilly Schilllung‐Stiftungs Professor, Neurobiology, University of Heidelberg


  • 1991: Habilitation and venia legendi, Faculty of Biology (Neurobiology), University of Heidelberg
  • 1985-2000: Group Leader in the Neurobiology, University of Heidelberg
  • 1982-1985: Postdoc with Drs. M. Smith and L. Steinman, Stanford University Medical Center, Dept. of Neurology, CA, USA
  • 1978-1982: Postdoc with Dr. E. Ferber, MPI for Immunobiology, Freiburg
  • 1974-1978: PhD with Dr. M. Rumsby, University of York, UK
  • 1974: Stagiare with the Health Protection Directorate of the European Union, Luxembourg/Brussels
  • 1973: BA in Biology with Chemistry, University of York, UK

Most relevant publications by Jacqueline Trotter

Sakry D, Yigit H, Dimou L and Trotter J (2015). Oligodendrocyte precursor cells synthesize neuromodulatory factors. PLoS One, 10, e0127222

Sakry D*, Neitz A*, Singh J, Frischknecht R, Marongiu D, Binamé F, Perera S, Endres K, Lutz B, Radyushkin K, Trotter  J# and Mittmann T# (2014). Oligodendrocyte precursor cells modulate the neuronal network by activity-dependent ectodomain cleavage of glial NG2. PLoS Biol, e1001993

Binamé F, Sakry D, Dimou L, Jolivel V and Trotter J (2013). NG2 regulates directional migration of Oligodendrocyte Precursor Cells via Rho GTPases and polarity complex proteins. In revision. J Neurosci, 33, 10858-10874

Sakry D, Karram K and Trotter J (2010). Synapses between NG2 glia and neurons. J Anat, 219, 2‐7

Trotter J, Karram K and Nishiyama A (2010). NG2 cells: properties, progeny and origin. Brain Res Rev, 63, 72‐82

Karram K, Goebbels S, Schwab M, Jennissen K, Seifert G, Steinhäuser C, Nave KA and Trotter J (2008). NG2‐expressing cells in the nervous system revealed by the NG2‐EYFP‐knockin mouse. Genesis, 46, 743‐757

Niehaus A, Stegmüller J, Diers‐Fenger M and Trotter J (1999). Cell‐surface glycoprotein of oligodendrocyte progenitors involved in migration. J Neurosci, 19, 4948‐4961

 (*indicates equal contribution, #indicates shared correspondence) 


  Research website