Targets of the NG2 intracellular domain in gene regulation in glial precursor cells

Research website

Positions held

  • Since 2000: Professor of Cell Biology (C3), Dept. of Biology, Johannes Gutenberg University (JGU), Mainz
  • 1999 - 2000: Hermann und Lilly Schilllung‐Stiftungs Professor, Neurobiology, University of Heidelberg

Education

  • 1991: Habilitation and venia legendi, Faculty of Biology (Neurobiology), University of Heidelberg
  • 1985 - 2000: Group Leader in the Neurobiology, University of Heidelberg
  • 1982 - 1985: Postdoc with Drs. M. Smith and L. Steinman, Stanford University Medical Center, Dept. of Neurology, CA, USA
  • 1978 - 1982: Postdoc with Dr. E. Ferber, MPI for Immunobiology, Freiburg
  • 1974 - 1978: PhD with Dr. M. Rumsby, University of York, UK
  • 1974: Stagiare with the Health Protection Directorate of the European Union, Luxembourg/Brussels
  • 1973: BA in Biology with Chemistry, University of York, UK

Selected publications by Jacqueline Trotter

Sakry D, Yigit H, Dimou L and Trotter J (2015) Oligodendrocyte precursor cells synthesize neuromodulatory factorsPLoS One, 10:e0127222 Link

Maus F, Sakry D, Binamé F, Karram K, Rajalingam K, Watts C, Heywood R, Krüger R, Stegmüller J, Werner HB, Nave KA, Krämer-Albers EM, Trotter J (2015) The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2. PLoS One, 10(9):e0137311 Link

Sakry D*, Neitz A*, Singh J, Frischknecht R, Marongiu D, Binamé F, Perera S, Endres K, Lutz B, Radyushkin K, Trotter  J# and Mittmann T# (2014) Oligodendrocyte precursor cells modulate the neuronal network by activity-dependent ectodomain cleavage of glial NG2. PLoS Biol, 12(11):e1001993 Link

Binamé F, Sakry D, Dimou L, Jolivel V, Trotter J (2013) NG2 regulates directional migration of oligodendrocyte precursor cells via Rho GTPases and polarity complex proteins. J Neurosci, 33(26):10858-74 Link

(*indicates equal contribution, #indicates shared correspondence)