Extracellular vesicles in cell communication


  • 2001: Group Leader, Molecular Cell Biology, Johannes Gutenberg University of Mainz
  • 2000: Postdoctoral Position, MPI of Experimental Medicine Göttingen
  • 1999: Postdoctoral Position, ZMBH, Ruprecht Karls University of Heidelberg


  • 2014: Habilitation and venia legendi in Cell Biology and Neurobiology, Faculty of Biology, Johannes Gutenberg University Mainz
  • 1994-1997: PhD, Institute of Neurobiology, Ruprecht Karls University of Heidelberg
  • 1992: Diploma in Biology, Ruprecht Karls University of Heidelberg

Most relevant publications by Eva-Maria Krämer-Albers

Krämer-Albers EM and Hill AF (2016). Extracellular vesicles: interneural shuttles of complex messages. Current Opin in Neurobiol, 39, 101-107

Frühbeis C, Helmig S, Tug S, Simon P and Krämer-Albers EM (2015). Physical exercise induces rapid release of small extracellular vesicles into the circulation.  J Extracell Vesicles, 4, 28239

Fröhlich D, Kuo WP, Frühbeis C, Sun JJ, Zehendner CM, Luhmann HJ, Pinto S, Toedling J, Trotter J and Krämer-Albers EM (2014). Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction, and gene regulation. Philos Trans R Soc Lond B Biol Sci, 369 doi: 10.1098/rstb.2013.0510

Frühbeis C, Fröhlich D, Kuo WP, Amphornrat J, Thilemann S, Saab AS, Kirchhoff F, Möbius M, Goebbels S, Nave KA, Schneider A, Simons M, Klugmann M, Trotter J, and Krämer-Albers EM (2013) Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication, PLOS Biol, 11, e1001604.

Frühbeis C, Fröhlich D and Krämer-Albers EM (2012). Emerging roles of exosomes in neuron-glia communication. Front Physiol, 3, 119

Feldmann A, Amphornrat J, Schönherr M, Winterstein C, Möbius W, Ruhwedel T, Danglot L, Nave KA, Galli T, Bruns D, Trotter J and Krämer-Albers EM (2011). Transport of the Major Myelin Protein PLP is Directed by the R-SNAREs VAMP3 and VAMP7. J Neurosci, 31, 5659-5672

Winterstein C, Trotter J and Krämer-Albers EM (2008). Distinct endocytic recycling of myelin proteins promotes oligodendroglial membrane remodeling. J Cell Sci, 121, 834-842

White R, Gonsior C, Krämer-Albers EM, Stöhr N, Hüttelmaier S and Trotter J (2008). Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2–dependent RNA granules. J Cell Biol, 181, 579-586

Krämer-Albers EM*, Bretz N, Winterstein C, Tenzer S, Möbius W, Nave KA, Schild H and Trotter J (2007). Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Proteomics Clin Appl 1, 1446-1461 *corresponding author

Krämer-Albers EM*, Gehrig-Burger K, Thiele C, Trotter J and Nave KA (2006). Perturbed Interactions of Mutant Proteolipid Protein/DM20 with Cholesterol and Lipid Rafts in Oligodendroglia: Implications for Dysmyelination in Spastic Paraplegia. J Neurosci, 26, 11743-11752 *corresponding author

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