Merbitz-Zahradnik T and Wolf E. (2015). How is the inner circadian clock controlled by interactive clock proteins? Structural analysis of clock proteins elucidates their physiological role. FEBS Lett, 589: 1516–1529. Link


Schmalen I, Reischl S, Wallach T, Klemz R, Grudziecki A, Prabu JR, Benda C, Kramer A and Wolf E. (2014). Interaction of circadian clock proteins CRY1 and PER2 is modulated by zinc binding and disulfide bond formation. Cell, 157: 1203–1215. Link

Witosch J, Wolf E and Mizuno N. (2014). Architecture and ssDNA interaction of the Timeless-Tipin-RPA complex. Nucleic Acids Res, 42: 12912–12927. Link


Czarna A, Berndt A, Singh HR, Grudziecki A, Ladurner AG, Timinszky G, Kramer A and Wolf E. (2013). Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function. Cell, 153: 1394–1405. Link

Makbul C, Constantinescu Aruxandei D, Hofmann E, Schwarz D, Wolf E and Herrmann C. (2013). Structural and thermodynamic characterization of Nore1-SARAH: A small, helical module important in signal transduction networks. Biochemistry, 52: 1045–1054. Link


Kucera N, Schmalen I, Hennig S, Ollinger R, Strauss HM, Grudziecki A, Wieczorek C, Kramer A and Wolf E. (2012). Unwinding the differences of the mammalian PERIOD clock proteins from crystal structure to cellular function. Proc Natl Acad Sci USA, 109: 3311–3316. Link


Czarna A*, Breitkreuz H*, Mahrenholz CC, Arens J, Strauss HM and Wolf E. (2011). Quantitative analyses of cryptochrome-mBMAL1 interactions: Mechanistic insights into the transcriptional regulation of the mammalian circadian clock. J Biol Chem, 286: 22414–22425. (*indicates joint contribution) Link

Pawlowski N, Khaminets A, Hunn JP, Papic N, Schmidt A, Uthaiah RC, Lange R, Vopper G, Martens S, Wolf E and Howard JC. (2011). The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii. BMC Biol, 9: 7. Link


Hennig S, Strauss HM, Vanselow K, Yildiz O, Schulze S, Arens J, Kramer A and Wolf E. (2009). Structural and functional analyses of PAS domain interactions of the clock proteins Drosophila PERIOD and mouse PERIOD2. PLoS Biol, 7: e94. Link

Landskron J, Chen KF, Wolf E and Stanewsky R. (2009). A role for the PERIOD: PERIOD homodimer in the Drosophila circadian clock. PLoS Biol, 7: e3. Link


Hoang N, Schleicher E, Kacprzak S, Bouly JP, Picot M, Wu W, Berndt A, Wolf E, Bittl R and Ahmad M. (2008). Human and Drosophila cryptochromes are light activated by flavin photoreduction in living cells. PLoS Biol, 6: e160. Link


Berndt A, Kottke T, Breitkreuz H, Dvorsky R, Hennig S, Alexander M and Wolf E. (2007). A novel photoreaction mechanism for the circadian blue light photoreceptor Drosophila cryptochrome. J Biol Chem, 282: 13011–13021. Link


Yildiz O, Doi M, Yujnovsky I, Cardone L, Berndt A, Hennig S, Schulze S, Urbanke C, Sassone-Corsi P and Wolf E. (2005). Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD. Mol Cell, 17: 69–82. Link