2019

Akhtar J, Kreim N, Marini F, Mohana G, Brüne D, Binder H and Roignant JY (2019) Promoter-proximal pausing mediated by the exon junction complex regulates splicing. Nat Commun, 10:521 Link

Hildebrandt A, Brüggemann M, Rücklé C, Boerner S, Heidelberger JB, Busch A, Hänel H, Voigt A, Möckel MM, Ebersberger S, Scholz A, Dold A, Schmid T, Ebersberger I, Roignant J-Y, Zarnack K#, König J# and Beli P# (2019) The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Genome Biol, 20:216 (#indicates joint correspondence) Link

Jacob D, Thüring K, Galliot A, Marchand V, Galvanin A, Ciftci A, Scharmann K, Stock M, Roignant JY, Leidel SA, Motorin Y, Schaffrath R, Klassen R and Helm M (2019) Absolute Quantification of Noncoding RNA by Microscale Thermophoresis. Angew Chemie Int Ed, 58:9565–9569 Link

Lence T, Paolantoni C, Worpenberg L and Roignant JY (2019) Mechanistic insights into m6A RNA enzymes. Biochim Biophys Acta - Gene Regul Mech, 1862:222–229 Link

Schützler N, Girwert C, Hügli I, Mohana G, Roignant JY, Ryglewski S and Duch C (2019) Tyramine action on motoneuron excitability and adaptable tyramine/octopamine ratios adjust Drosophila locomotion to nutritional state. Proc Natl Acad Sci USA, 116:3805–3810 Link

Worpenberg L, Jakobi T, Dieterich C and Roignant JY (2019) Identification of methylated transcripts using the TRIBE approach. Pages 89–106 in: Epitranscriptomics; Methods in molecular biology, vol. 1870 (eds. Wajapeyee N & Gupta R), Humana Press, New York Link

2018

Angelova MT*, Dimitrova DG*, Dinges N*, Lence T*, Worpenberg L*, Carré C# and Roignant JY# (2018) The emerging field of epitranscriptomics in neurodevelopmental and neuronal disorders. Front Bioeng Biotechnol, 6:46 (*indicates joint contribution, #indicates joint correspondence) Link

Becker K, Bluhm A*, Casas-Vila N*, Dinges N*, Dejung M, Sayols S, Kreutz C, Roignant JY, Butter F# and Legewie S# (2018) Quantifying post-transcriptional regulation in the development of Drosophila melanogaster. Nat Commun, 9:4970 (*indicates joint contribution, #indicates joint correspondence) Link

de Brouwer APM*, Abou Jamra R*, Körtel N*, Soyris C, Polla DL, Safra M, Zisso A, Powell CA, Rebelo-Guiomar P, Dinges N, Morin V, Stock M, Hussain M, Shahzad M, Riazuddin S, Ahmed ZM, Pfundt R, Schwarz F, de Boer L, Reis A, Grozeva D, Raymond FL, Riazuddin S, Koolen DA, Minczuk M, Roignant JY#, van Bokhoven H# and Schwartz S# (2018) Variants in PUS7 cause intellectual disability with speech delay, microcephaly, short stature, and aggressive behavior. Am J Hum Genet, 103:1045–1052 (*indicates joint contribution, #indicates joint correspondence) Link

Dold A*, Han H*, Liu N*, Hildebrandt A, Brüggemann M, Rücklé C, Busch A, Beli P, Zarnack K, König J, Roignant JY# and Lasko P# (2018) Makorin 1 controls embryonic patterning by alleviating Bruno-mediated repression of oskar translation. BioRxiv, doi: 10.1101/501643 (*indicates joint contribution, #indicates joint correspondence) Link

Jantsch MF, Quattrone A, O’Connell M, Helm M, Frye M, Macias-Gonzales M, Ohman M, Ameres S, Willems L, Fuks F, Oulas A, Vanacova S, Nielsen H, Bousquet-Antonelli C, Motorin Y, Roignant JY, Balatsos N, Dinnyes A, Baranov P, Kelly V, Lamm A, Rechavi G, Pelizzola M, Liepins J, Kholodnyuk IH, Zammit V, Ayers D, Drablos F, Dahl JA, Bujnicki J, Jeronimo C, Almeida R, Neagu M, Costache M, Bankovic J, Banovic B, Kyselovic J, Valor LM, Selbert S, Pir P, Demircan T, Cowling V, Schäfer M, Rossmanith W, Lafontaine D, David A, Carre C, Lyko F, Schaffrath R, Schwartz S, Verdel A, Klungland A, Purta E, Timotijevic G, Cardona F, Davalos A, Ballana E, O´Carroll D, Ule J and Fray R (2018) Positioning Europe for the EPITRANSCRIPTOMICS challenge. RNA Biol, 15:829–831 Link

Knuckles P*, Lence T*, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, Biggiogera M, Helm M, Soller M, Bühler M and Roignant JY (2018) Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d. Genes Dev, 32:415–429 (*indicates joint contribution) Link

2017

Casas-Vila N*, Bluhm A*, Sayols S*, Dinges N, Dejung M, Altenhein T, Kappei D, Altenhein B, Roignant JY and Butter F (2017) The developmental proteome of Drosophila melanogaster. Genome Res, 27:1273–1285 (*indicates joint contribution) Link

Dinges N, Morin V, Kreim N, Southall TD and Roignant JY (2017) Comprehensive characterization of the complex lola locus reveals a novel role in the octopaminergic pathway via tyramine beta-hydroxylase regulation. Cell Rep, 21:2911–2925 Link

Lence T, Soller M and Roignant JY (2017) A fly view on the roles and mechanisms of the m6A mRNA modification and its players. RNA Biol, 14:1232–1240 Link

Roignant JY and Soller M (2017) m(6)A in mRNA: An Ancient Mechanism for Fine-Tuning Gene Expression. Trends Genet, 33:380–390 Link

2016

Lence T, Akhtar J, Bayer M, Schmid K, Spindler L, Ho CH, Kreim N, Andrade-Navarro MA, Poeck B, Helm M and Roignant JY (2016) m6A modulates neuronal functions and sex determination in Drosophila. Nature, 540:242–247 Link

Żurek-Biesiada D, Szczurek AT, Prakash K, Best G, Mohana GK, Lee H-K, Roignant JY, Dobrucki JW, Cremer C and Birk U (2016) Quantitative super-resolution localization microscopy of DNA in situ using Vybrant®DyeCycleTM Violet fluorescent probe. Data Br, 7:157–171 Link

Zurek-Biesiada D, Szczurek AT, Prakash K, Mohana GK, Lee HK, Roignant JY, Birk UJ, Dobrucki JW and Cremer C (2016) Localization microscopy of DNA in situ using Vybrant® DyeCycleTM Violet fluorescent probe: A new approach to study nuclear nanostructure at single molecule resolution. Exp Cell Res, 343:97–106 Link

2014

Malone CD, Mestdagh C, Akhtar J, Kreim N, Deinhard P, Sachidanandam R, Treisman J and Roignant JY (2014) The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript. Genes Dev, 28:1786–1799 Link

2010

Roignant JY, Legent K, Janody F and Treisman JE (2010) The transcriptional co-factor Chip acts with LIM-homeodomain proteins to set the boundary of the eye field in Drosophila. Development, 137:273–281 Link

Roignant JY and Treisman JE (2010) Exon junction complex subunits are required to splice Drosophila MAP Kinase, a large heterochromatic gene. Cell, 143:238–250 Link

2009

Roignant JY and Treisman JE (2009) Pattern formation in the Drosophila eye disc. Int J Dev Biol, 53:795–804 Link

2008

Miura GI, Roignant JY, Wassef M and Treisman JE (2008) Myopic acts in the endocytic pathway to enhance signaling by the Drosophila EGF receptor. Development, 135:1913–1922 Link

2006

Roignant JY, Hamel S, Janody F and Treisman JE (2006) The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathway. Genes Dev, 20:795–806 Link

2003

Faucheux M, Roignant JY, Netter S, Charollais J, Antoniewski C and Théodore L (2003) batman Interacts with polycomb and trithorax group genes and encodes a BTB/POZ protein that is included in a complex containing GAGA factor. Mol Cell Biol, 23:1181–1195 Link

Roignant JY (2003) Absence of transitive and systemic pathways allows cell-specific and isoform-specific RNAi in Drosophila. RNA, 9:299–308 Link