Acebron SP and Niehrs C (2016). β-catenin-independent roles of Wnt/LRP6 signaling. Trends Cell Biol, 26, 956-967 

Boutros M and Niehrs C (2016). Sticking around: Short-range activity of Wnt ligands. Dev Cell, 36, 485-486

Kaaij LJ, Mokry M, Zhou M, Musheev M, Geeven G, Melquiond AS, de Jesus Domingues AM, de Laat W, Niehrs C, Smith AD and Ketting RF (2016). Enhancers reside in a unique epigenetic environment during early zebrafish development. Genome Biol, 17, 146

Scholz B, Korn C, Wojtarowicz J, Mogler C, Augustin I, Boutros M, Niehrs C and Augustin HG (2016). Endothelial RSPO3 controls vascular stability and pruning through non-canonical WNT/Ca(2+)/ NFAT signaling. Dev Cell, 36, 79-93

Schomacher L, Han D, Musheev M, Kienhöfer S, von Seggern A and Niehrs C (2016). NEIL DNA  glycosylases coordinate substrate handover during oxidative DNA demethylation. Nat Struct Mol Biol, 23, 116-124

Blum M, De Robertis EM, Wallingford JB and Niehrs C (2015). Morpholinos: Anti-sense and sensibility. Dev Cell, 2, 145-149

Fukusumi Y,  Meier F, Götz S, Matheus F, Irmler M, Beckervordersandforth R, Faus-Kessler T, Minina E, Rauser B, Zhang J, Arenas E, Andersson E, Niehrs C, Beckers J, Simeone A, Wurst W and Prakash N (2015). Dickkopf 3 promotes the differentiation of a rostrolateral midbrain dopaminergic neuronal subset in vivo and from pluripotent stem cells in vitro in the mouse. J Neurosci, 35, 13385-13401

Huang YL, Anvarian Z, Döderlein G, Acebron S and Niehrs C (2015). Maternal Wnt/STOP signaling promotes cell division during early Xenopus embryogenesis. Proc Natl Acad Sci U S A, 112, 5732-5737

Kienhöfer S, Musheev MU, Stapf U, Helm M, Schomacher L, Niehrs C and Schäfer A (2015). GADD45a physically and functionally interacts with TET1. Differentiation, 90, 59-68

Kimura-Yoshida C, Mochida K, Ellwanger K, Niehrs C and Matsuo I (2015). Fate specification of neural plate border by canonical Wnt signaling and Grhl3 is crucial for neural tube closure. EBioMedicine, 2, 513-527

Koch S, Acebron SP, Herbst J, Hatiboglu G and Niehrs C (2015). Posttranscriptional Wnt signaling governs epididymal sperm maturation. Cell, 163, 1225-1236

Lelle M, Kaloyanova S, Freidel C, Theodoropoulou M, Musheev M, Niehrs C, Stalla G and Peneva K (2015). Octreotide-mediated tumor-targeted drug delivery via a cleavable doxorubicin-peptide conjugate. Mol Pharm, 12, 4290-3000

Welling M, Chen HH, Muñoz J, Musheev MU, Kester L, Junker JP, Mischerikow N, Arbab M, Kuijk E, Silberstein L, Kharchenko PV, Geens M, Niehrs C, van de Velde H, van Oudenaarden A, Heck AJ and Geijsen N (2015). DAZL regulates Tet1 translation in murine embryonic stem cells. EMBO Rep, 16, 791-802

Arab K, Park YJ, Lindroth AM, Schäfer A, Oakes C, Weichenhan D, Lukanova A, Lundin E, Risch A, Meister M, Dienemann H, Dyckhoff G, Herold-Mende C, Grummt I#, Niehrs C# and Plass C# (2014). Long Noncoding RNA TARID Directs Demethylation and Activation of the Tumor Suppressor TCF21 via GADD45A. Mol Cell, 55, 604-614 (#indicates joint correspondence)

De Robertis EM and Niehrs C (2014). Herbert Steinbeisser: a life with the Xenopus embryo. Int J Dev Biol, 58, 299-302

Huang YL and Niehrs C (2014). Polarized Wnt Signaling Regulates Ectodermal Cell Fate in Xenopus. Dev Cell, 29, 250-257

Niehrs C (2014). Chromatin Dynamics and Stem Cells. In Jahrbuch 2013 der Deutschen Akademie der Naturforscher Leopoldina (Halle/Saale) LEOPOLDINA, 59, 445-449

Perez-Acebron S, Karaulanov E, Berger BS, Huang YL and Niehrs C (2014). Mitotic Wnt signaling promotes protein stabilization and regulates cell size. Mol Cell, 54, 663-774

Simonetti M, Agarwal N, Stösser S, Bali KK, Karaulanov E, Kamble R, Pospisilova B, Kurejova M, Birchmeier W, Niehrs C, Heppenstall P and Kuner R (2014). Wnt-Fzd signaling sensitizes peripheral sensory neurons via distinct noncanonical pathways. Neuron, 83, 104-121

Cruciat CM, Dolde C, de Groot RE, Ohkawara B, Reinhard C, Korswagen HC, Niehrs C (2013). RNA helicase DDX3 is a regulatory subunit of casein kinase 1 in Wnt-β-catenin signaling. Science, 339, 1436-1441

Cruciat CM and Niehrs C (2013). Secreted and transmembrane Wnt inhibitors and activators. Cold Spring Harb Perspect Biol, 3, a015081

Demir K, Kirsch N, Beretta CA, Erdmann G, Ingelfinger D, Moro E, Argenton F, Carl M, Niehrs C, Boutros M (2013). RAB8B Is Required for Activity and Caveolar Endocytosis of LRP6. Cell Rep, 4, 1224-1234

Niehrs C (2013). DNA Demethylation, Repair and Beyond. In Jahrbuch 2012 der Deutschen Akademie der Naturforscher Leopoldina (Halle/Saale) LEOPOLDINA, 58, 387-391

Romero D, Kawano Y, Bengoa N, Walker MM, Maltry N, Niehrs C, Waxman J, Kypta R (2013). Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-b/Smad signaling. J Cell Science, 126, 1858-1867

Schäfer A, Karaulanov E, Stapf U, Döderlein G and Niehrs C (2013). Ing1 functions in DNA demethylation by directing Gadd45a to H3K4me3. Genes Dev, 27, 261-273

Seib DR, Corsini NS, Ellwanger K, Plaas C, Mateos A, Pitzer C, Niehrs C, Celikel T, Martin-Villalba A (2013). Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline. Cell Stem Cell, 12, 204-214

El Wakil A, Guya N, Bandulikc S, Bendahhoub S, Zennaroe MC, Niehrs C, Maria B, Warth R, Barhanin J and Lallia E (2012). Dkk3 is a component of the genetic circuitry regulating expression of the Cyp11b2 rate-limiting enzyme of aldosterone synthesis in the adrenal cortex. Hum Mol Genet, 21, 4922-4929

Gierl MS, Gruhn WH, von Seggern A, Maltry N and Niehrs C (2012). Gadd45g functions in male sex determination by promoting p38 signaling and Sry expression. Dev Cell, 23, 1032-1042

Niehrs C (2012). The complex world of WNT receptor signalling. Nat Rev Mol Cell Biol, 13, 767-779

Niehrs C and Acebron SP (2012). Mitotic and mitogenic Wnt signalling. EMBO J, 31, 2705-2713

Niehrs C and Schäfer A (2012). Active DNA demethylation by Gadd45 and DNA repair. Trends Cell Biol, 22, 220-227

Papatriantafyllou M, Moldenhauer G, Ludwig J, Tafuri A, Garbi N, Hollmann G, Küblbeck G, Klevenz A, Schmitt S, Pougialis G, Niehrs C, Gröne HJ, Hämmerling GJ, Arnold B and Oelert T (2012). Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance. Proc Natl Acad Sci U S A, 109, 1631-1636

Teufel A, Becker D, Weber SN, Dooley S, Breitkopf-Heinlein K, Maass T, Hochrath K, Krupp M, Marquardt JU, Kolb M, Korn B, Niehrs C, Zimmermann T, Galle PR and Lammert F (2012). Identification of RARRES1 as a core regulator in liver fibrosis. J Mol Med, 90, 1439-1447

Glinka A, Dolde C, Kirsch N, Huang YL, Kazanskaya O, Ingelfinger D, Boutros M, Cruciat CM and Niehrs C (2011). LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling. EMBO Rep, 12, 1055-1061

Huhn S, Ingelfinger D, Bermejo JL, Bevier M, Pardini B, Naccarati A, Steinke V, Rahner N, Holinski-Feder E, Morak M, Schackert HK, Görgens H, Pox CP, Goecke T, Kloor M, Loeffler M, Büttner R, Vodickova L, Novotny J, Demir K, Cruciat CM, Renneberg R, Huber W, Niehrs C, Boutros M, Propping P, Vodièka P, Hemminki K and Försti A (2011). Polymorphisms in CTNNBL1 in relation to colorectal cancer with evolutionary implications. Int J Mol Epidemiol Genet, 2, 36-50

Kaufmann LT and Niehrs C (2011). Gadd45a, Gadd45b and Gadd45g expression during mouse embryonic development. Gene Expr Patterns, 11, 465-470

Kaufmann LT and Niehrs C (2011). Gadd45a and Gadd45g regulate neural development and exit from pluripotency in Xenopus. Mech Dev, 128, 401-411

Liang J, Fu Y, Cruciat CM, Jia S, Wang Y, Tong Z, Tao Q, Ingelfinger D, Boutros M, Meng A, Niehrs C and Wu W (2011). Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation. Mol Cell Biol, 31, 2577-2590

Niehrs C (2011). Dialectics, systems biology and embryonic induction. Differentiation, 81, 209-216

Ohkawara B, Glinka A and Niehrs C (2011). Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis. Dev Cell, 20, 303-314

Paulsen M*, Legewie S*, Eils R, Karaulanov E and Niehrs C (2011). Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development. Proc Natl Acad Sci U S A, 108, 10202-10207 (*indicates joint contribution)

Pietilä I, Ellwanger K, Railo A, Jokela T, Barrantes Idel B, Shan J, Niehrs C and Vainio SJ (2011). Secreted Wnt antagonist Dickkopf-1 controls kidney papilla development coordinated by Wnt-7b signalling. Dev Biol, 353, 50-60

Ribeiro D, Ellwanger K, Glagow D, Theofilopoulos S, Corsini NS, Martin-Villalba A, Niehrs C and Arenas E (2011). Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis. PLoS One, 6, e15786

Rousso SZ, Schyr RB, Gur M, Zouela N, Kot-Leibovich H, Shabtai Y, Koutsi-Urshanski N, Baldessari D, Pillemer G, Niehrs C and Fainsod A (2011). Negative autoregulation of Oct3/4 through Cdx1 promotes the onset of gastrulation. Dev Dyn, 240, 796-807

Sytnikova YA, Kubarenko AV, Schäfer A, Weber ANR and Niehrs C (2011). Gadd45a is an RNA binding protein and is localized in nuclear speckles. PLoS One, 6, e14500

Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spirohn K, Niehrs C and Boutros M (2010). Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol, 20, 1263-1268

Cruciat CM, Ohkawara B, Acebron SP, Karaulanov E, Reinhard C, Ingelfinger D, Boutros M and Niehrs C (2010). Requirement of prorenin receptor and Vacuolar H+-ATPase-Mediated Acidification for Wnt Signaling. Science, 327, 459-463

Davidson G and Niehrs C (2010). Emerging links between CDK cell cycle regulators and Wnt signaling. Trends Cell Biol, 20, 453-460   

Niehrs C (2010). On growth and form: a Cartesian coordinate system of Wnt and BMP signaling specifies bilaterian body axes. Dev, 137, 845-857

Niehrs C and Acebron SP (2010). Wnt signaling: multivesicular bodies hold GSK3 captive. Cell, 143, 1044-1046

Niehrs C and Boutros M (2010). Trafficking, acidification, and growth factor signaling. Sci Signal, 3, 26

Niehrs C and Shen JL (2010). Regulation of Lrp6 phosphorylation. Cell Mol Life Sci, 67, 2551-2562

Ohkawara B and Niehrs C (2010). An ATF2-based luciferase reporter to monitor non-canonical Wnt signaling in Xenopus embryos. Dev Dyn, 240, 188-194

Schäfer A, Schomacher L, Barreto G, Döderlein G and Niehrs C (2010). Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation. PLoS One, 5, e14060

Schulze J, Seitz S, Saito H, Schneebauer M, Marshall RP, Baranowsky A, Busse B, Schilling AF, Friedrich FW, Albers J, Spiro AS, Zustin J, Streichert T, Ellwanger K, Niehrs C, Amling M, Baron R and Schinke T (2010). Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2. PLoS One, 5, e10309

Wang Y, Fu Y, Gao L, Zhu GX, Liang J, Gao C, Huang BL, Fenger U, Niehrs C, Chen YG and Wu W (2010). Xenopus skip modulates Wnt/beta-catenin signaling and functions in neural crest induction. J Biol Chem, 285, 10890-10901  

Davidson G, Shen JL, Huang YL, Su Y, Karaulanov E, Bartscherer K, Hassler C, Stannek P, Boutros M and Niehrs C (2009). Cell cycle control of Wnt receptor activation. Dev Cell, 17, 788-799

Karaulanov E, Böttcher RT, Stannek P, Wu W, Rau M, Ogata S, Cho KWY and Niehrs C (2009). Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos. PLoS One, 4, e5742

Niehrs C (2009). Dialektik der embryonalen Induktion. Jahrbuch Heidelb Akad Wiss, 42-61

Niehrs C (2009). Active DNA demethylation and DNA repair. Differentiation, 77, 1-11

Ellwanger K, Saito H, Clement-Lacroix P, Maltry N, Niedermeyer J, Lee WK, Baron R, Rawadi G, Westphal H and Niehrs C (2008). Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density. Mol Cell Biol, 28, 4875-4882

Kazanskaya O, Ohkawara B, Heroult M, Wu W, Maltry N, Augustin HG and Niehrs C (2008). The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. Development, 135, 3655-3664

Barreto G, Schafer A, Marhold J, Stach D, Swaminathan SK, Handa V, Doderlein G, Maltry N, Wu W, Lyko F and Niehrs C (2007). Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature, 445, 671-675

Bilic J, Huang YL, Davidson G, Zimmermann T, Cruciat CM, Bienz M and Niehrs C (2007). Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science, 316, 1619-1622

Caneparo L, Huang YL, Staudt N, Tada M, Ahrendt R, Kazanskaya O, Niehrs C and Houart C (2007). Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. Genes Dev, 21, 465-480

Carmona-Fontaine C, Acuna G, Ellwanger K, Niehrs C and Mayor R (2007). Neural crests are actively precluded from the anterior neural fold by a novel inhibitory mechanism dependent on Dickkopfl secreted by the prechordal mesoderm. Dev Biol, 309, 208-221

Hassler C, Cruciat CM, Huang YL, Kuriyama S, Mayor R and Niehrs C (2007). Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling. Development, 134, 4255-4263

Ogata S, Morokuma J, Hayata T, Kolle G, Niehrs C, Ueno N and Cho KWY (2007). TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. Genes Dev, 21, 1817-1831

Pinho S and Niehrs C (2007). Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction. Differentiation, 75, 957-967