2019

Balmus G, Pilger D, Coates J, Demir M, Sczaniecka-Clift M, Barros AC, Woods M, Fu B, Yang F, Chen E, Ostermaier M, Stankovic T, Ponstingl H, Herzog M, Yusa K, Martinez FM, Durant ST, Galanty Y, Beli P, Adams DJ, Bradley A, Metzakopian E, Forment J V and Jackson SP (2019) ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks. Nat Commun, 10:87 Link

Dold A, Han H, Liu N, Hildebrandt A, Brüggemann M, Rücklé C, Busch A, Beli P, Zarnack K, König J, Roignant JY and Lasko P (2019) Makorin 1 controls embryonic patterning by alleviating Bruno-mediated repression of oskar translation. bioRxiv, doi: 10.1101/501643 Link

Hildebrandt A, Brüggemann M, Rücklé C, Boerner S, Heidelberger JB, Busch A, Hänel H, Voigt A, Möckel MM, Ebersberger S, Scholz A, Dold A, Schmid T, Ebersberger I, Roignant J-Y, Zarnack K#, König J# and Beli P# (2019) The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation. Genome Biol, 20:216 (#indicates joint correspondence) Link

Juretschke T, Beli P and Dikic I (2019) Quantitative phosphoproteomics of selective autophagy receptors. Pages 691–701 in: Autophagy; Methods in Molecular Biology, vol. 1880 (eds. Ktistakis N & Florey O), Humana Press, New York Link

Sasca D, Szybinski J, Schüler A, Shah V, Heidelberger J, Haehnel PS, Dolnik A, Kriege O, Fehr E-M, Gebhardt WH, Reid G, Scholl C, Theobald M, Bullinger L, Beli P and Kindler T (2019) Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in AML. Blood, 133:2305–2319 Link

2018

Borisova ME, Voigt A, Tollenaere MAX, Sahu SK, Juretschke T, Kreim N, Mailand N, Choudhary C, Bekker-Jensen S, Akutsu M, Wagner SA and Beli P (2018) p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage. Nat Commun, 9:1017 Link

Dev H, Chiang T-WW, Lescale C, de Krijger I, Martin AG, Pilger D, Coates J, Sczaniecka-Clift M, Wei W, Ostermaier M, Herzog M, Lam J, Shea A, Demir M, Wu Q, Yang F, Fu B, Lai Z, Balmus G, Belotserkovskaya R, Serra V, O’Connor MJ, Bruna A, Beli P, Pellegrini L, Caldas C, Deriano L, Jacobs JJL, Galanty Y and Jackson SP (2018) Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells. Nat Cell Biol, 20:954–965 Link

Heidelberger JB, Voigt A, Borisova ME, Petrosino G, Ruf S, Wagner SA and Beli P (2018) Proteomic profiling of VCP substrates links VCP to K6‐linked ubiquitylation and c‐Myc function. EMBO Rep, 19:e44754 Link

2017

Borisova ME, Wagner SA and Beli P (2017) Mass spectrometry-based proteomics for quantifying DNA damage-induced phosphorylation. Pages 215–227 in: ATM Kinase; Methods in Molecular Biology, vol. 1599 (ed. Walker J), Humana Press, New York Link

Diamanti MA, Gupta J, Bennecke M, De Oliveira T, Ramakrishnan M, Braczynski AK, Richter B, Beli P, Hu Y, Saleh M, Mittelbronn M, Dikic I and Greten FR (2017) IKKα controls ATG16L1 degradation to prevent ER stress during inflammation. J Exp Med, 214:423–437 Link

Hildebrandt A, Alanis-Lobato G, Voigt A, Zarnack K, Andrade-Navarro MA, Beli P# and König J# (2017) Interaction profiling of RNA-binding ubiquitin ligases reveals a link between posttranscriptional regulation and the ubiquitin system. Sci Rep, 7:16582 (#indicates joint correspondence) Link

Mahendrarajah N, Borisova ME, Reichardt S, Godmann M, Sellmer A, Mahboobi S, Haitel A, Schmid K, Kenner L, Heinzel T, Beli P and Krämer OH (2017) HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3. Cell Signal, 39:9–17 Link

Sahu SK, Tiwari N, Pataskar A, Zhuang Y, Borisova M, Diken M, Strand S, Beli P and Tiwari VK (2017) FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development. Nat Commun, 8:1523 Link

Schunter S, Villa R, Flynn V, Heidelberger JB, Classen AK, Beli P and Becker PB (2017) Ubiquitylation of the acetyltransferase MOF in Drosophila melanogaster. PLOS One, 12:e0177408 Link

2016

Heidelberger JB, Wagner SA and Beli P (2016) Mass spectrometry-based proteomics for investigating DNA damage-associated protein ubiquitylation. Front Genet, 7:109 Link

Richter B, Sliter DA, Herhaus L, Stolz A, Wang C, Beli P, Zaffagnini G, Wild P, Martens S, Wagner SA, Youle RJ and Dikic I (2016) Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria. Proc Natl Acad Sci USA, 113:4039–4044 Link

Wagner SA, Oehler H, Voigt A, Dalic D, Freiwald A, Serve H and Beli P (2016) ATR inhibition rewires cellular signaling networks induced by replication stress. Proteomics, 16:402–416 Link

Wagner SA, Satpathy S, Beli P and Choudhary C (2016) SPATA2 links CYLD to the TNF-alpha receptor signaling complex and modulates the receptor signaling outcomes. EMBO J, 35:1868–1884 Link

2015

Beli P and Jackson SP (2015) Ubiquitin regulates dissociation of DNA repair factors from chromatin. Oncotarget, 6:14727–14728 Link

Brown JS, Lukashchuk N, Sczaniecka-Clift M, Britton S, le Sage C, Calsou P, Beli P#, Galanty Y# and Jackson SP# (2015) Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites. Cell Rep, 11:704–714 (#indicates joint correspondence) Link

Bursomanno S*, Beli P*, Khan AM, Minocherhomji S, Wagner SA, Bekker-Jensen S, Mailand N, Choudhary C, Hickson ID and Liu Y (2015) Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells. DNA Repair, 25:84–96 (*indicates joint contribution) Link

Chu WK, Payne MJ, Beli P, Hanada K, Choudhary C and Hickson ID (2015) FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51. Nat Commun, 6:5931 Link

Gallina I, Colding C, Henriksen P, Beli P, Nakamura K, Offman J, Mathiasen DP, Silva S, Hoffmann E, Groth A, Choudhary C and Lisby M (2015) Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. Nat Commun, 6:6533 Link

Satpathy S, Wagner SA, Beli P, Gupta R, Kristiansen TA, Malinova D, Francavilla C, Tolar P, Bishop GA, Hostager BS and Choudhary C (2015) Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation. Mol Syst Biol, 11:810 Link

Schmidt CK, Galanty Y, Sczaniecka-Clift M, Coates J, Jhujh S, Demir M, Cornwell M, Beli P and Jackson SP (2015) Systematic E2 screening reveals a UBE2D–RNF138–CtIP axis promoting DNA repair. Nat Cell Biol, 17:1458–1470 Link

Schölz C, Weinert BT, Wagner SA, Beli P, Miyake Y, Qi J, Jensen LJ, Streicher W, McCarthy AR, Westwood NJ, Lain S, Cox J, Matthias P, Mann M, Bradner JE and Choudhary C (2015) Acetylation site specificities of lysine deacetylase inhibitors in human cells. Nat Biotechnol, 33:415–423 Link

Tollenaere MAX, Villumsen BH, Blasius M, Nielsen JC, Wagner SA, Bartek J, Beli P, Mailand N and Bekker-Jensen S (2015) p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1. Nat Commun, 6:10075 Link

Yang J, Wagner SA and Beli P (2015) Illuminating spatial and temporal organization of protein interaction networks by mass spectrometry-based proteomics. Front Genet, 6:344 Link

2014

Oka Y, Varmark H, Vitting-Seerup K, Beli P, Waage J, Hakobyan A, Mistrik M, Choudhary C, Rohde M, Bekker-Jensen S and Mailand N (2014) UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells. EMBO Rep, 15:956–964 Link

2013

Villumsen BH, Danielsen JR, Povlsen L, Sylvestersen KB, Merdes A, Beli P, Yang Y-G, Choudhary C, Nielsen ML, Mailand N and Bekker-Jensen S (2013) A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis. EMBO J, 32:3029–3040 Link

Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T and Choudhary C (2013) Acetyl-phosphate is a critical determinant of lysine acetylation in E. coli. Mol Cell, 51:265–272 Link

2012

Beli P*, Lukashchuk N*, Wagner SA, Weinert BT, Olsen J V., Baskcomb L, Mann M, Jackson SP and Choudhary C (2012) Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response. Mol Cell, 46:212–225 (*indicates joint contribution) Link

Mosbech A, Gibbs-Seymour I, Kagias K, Thorslund T, Beli P, Povlsen L, Nielsen SV, Smedegaard S, Sedgwick G, Lukas C, Hartmann-Petersen R, Lukas J, Choudhary C, Pocock R, Bekker-Jensen S and Mailand N (2012) DVC1 (C1orf124) is a DNA damage–targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks. Nat Struct Mol Biol, 19:1084–1092 Link

Povlsen LK*, Beli P*, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N and Choudhary C (2012) Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Nat Cell Biol, 14:1089–1098 (*indicates joint contribution) Link

Wagner SA*, Beli P*, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen J V., Brakebusch C and Choudhary C (2012) Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Mol Cell Proteomics, 11:1578–1585 (*indicates joint contribution) Link

2011

Wagner SA*, Beli P*, Weinert BT, Nielsen ML, Cox J, Mann M and Choudhary C (2011) A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Mol Cell Proteomics, 10:M111.013284 (*indicates joint contribution) Link

2008

Beli P, Mascheroni D, Xu D and Innocenti M (2008) WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2. Nat Cell Biol, 10:849–857 Link